颅内动脉瘤介入治疗的疗效评价

发布时间：2018-03-10 16:12

本文选题：颅内动脉瘤　切入点：介入治疗　出处：《昆明医科大学》2015年硕士论文　论文类型：学位论文

【摘要】：研究背景颅内动脉瘤是颅内动脉管壁的局限性异常膨出,在脑血管疾病病因中位居第3位,是造成蛛网膜下腔出血(subarachnoid hemorrhage,SAH)的首位病因,其死亡率和致残率很高。随着介入技术和介入材料的不断发展,血管内治疗已成为颅内动脉瘤的首选治疗方法。但是,介入治疗作为一种微创技术,其手术风险仍然无法避免,如术中动脉瘤破裂、血栓事件及复发等。本研究对我科2年来收治的100例病例进行回顾性分析,探讨颅内动脉瘤介入治疗的疗效。研究目的分析介入治疗颅内动脉瘤的手术并发症发生率、临床及影像学结果、动脉瘤影像随访再通率,探讨颅内动脉瘤介入治疗的疗效及如何更好地进行颅内动脉瘤的介入治疗。研究方法对我科2年来收治的100例病例进行回顾性分析。将收集的数据制作成SPSS数据,对临床及影像学资料进行归纳总结,分析总体疗效。根据动脉瘤栓塞程度进行分组,比较多组间影像学随访结果差异。所有统计资料用SPSS13.0统计分析系统进行分析,当P0.05时差异有统计学意义。研究结果100例患者,127枚动脉瘤,栓塞术后即刻造影,102枚致密栓塞,14枚瘤颈残瘤,11枚部分栓塞。术中动脉瘤破裂11例,器械相关并发症4例。研究结论血管内治疗作为颅内动脉瘤的首选治疗方法是安全、有效的,但仍然有风险,如术中动脉瘤破裂,术中或术后血栓形成,术后再通等。要想提高介入治疗的疗效,尽量减少或避免术中及术后并发症的发生,就要采取积极的预防措施,最大努力地做好围手术期处理,另外,术中根据动脉瘤的具体部位、形态、大小及其与载瘤动脉的关系而采用适合的介入治疗方法是至关重要的。
[Abstract]:Background Intracranial aneurysm is the local abnormal bulge of intracranial artery wall, which is the third cause of cerebrovascular disease and the first cause of subarachnoid hemorrhage (SAH). With the continuous development of interventional technology and interventional materials, endovascular treatment has become the first choice for the treatment of intracranial aneurysms. However, as a minimally invasive technique, the surgical risk of interventional therapy is still unavoidable. In this study, 100 cases of aneurysm rupture, thrombus and recurrence in our department were retrospectively analyzed. Objective to investigate the effect of interventional therapy on intracranial aneurysms. To explore the curative effect of interventional treatment of intracranial aneurysms and how to better carry out interventional treatment of intracranial aneurysms. Methods 100 cases of intracranial aneurysms treated in our department in the past 2 years were retrospectively analyzed. The collected data were made into SPSS data. The clinical and imaging data were summarized and the overall curative effect was analyzed. According to the degree of embolism of aneurysm, the difference of imaging follow-up results among different groups was compared. All statistical data were analyzed by SPSS13.0 statistical analysis system. Results there were 127 aneurysms in 100 patients and 11 partial embolization of 14 cervical residual tumors in 102 dense embolization cases immediately after embolization. 11 cases of aneurysms ruptured during the operation. Conclusion Endovascular therapy is safe and effective as the first choice for the treatment of intracranial aneurysms, but there are still risks, such as rupture of aneurysms during operation, thrombosis during or after operation. If we want to improve the curative effect of interventional therapy and minimize or avoid complications during and after operation, we should take active preventive measures and do our utmost to handle the perioperative period well. In addition, It is very important to adopt appropriate interventional therapy according to the location, shape, size of aneurysm and its relationship with the aneurysm carrier artery.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R743

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