H型高血压与缺血性脑卒中血管狭窄的相关性研究

发布时间：2018-03-12 18:23

本文选题：脑卒中　切入点：血管狭窄　出处：《河南医学研究》2014年01期 　论文类型：期刊论文

【摘要】：目的:探讨H型高血压与缺血性脑卒中血管狭窄的相关性。方法:选取郑州大学第一附属医院神经内科收治的365例缺血性脑卒中血管狭窄患者作为研究对象,根据血管狭窄程度将其分为轻度狭窄、中度狭窄、重度狭窄3组,同时测定血压、血清同型半胱氨酸水平,并进行相关性分析。结果:高血压和缺血性脑卒中血管狭窄程度有关联,差异有统计学意义(r=0.498,P0.05)。不同血管狭窄程度间同型半胱氨酸水平进行比较,差异有统计学意义(P0.05)。高血压及高同型半胱氨酸血症之间存在正相加的交互作用(S=1.831)。H型高血压与血管狭窄部位无明显相关性(P0.05)。结论:高血压、同型半胱氨酸均为引起血管狭窄的独立危险因素,且随着血压及同型半胱氨酸的增高,血管狭窄程度也逐渐增高,高血压和高同型半胱氨酸血症具有协同作用。H型高血压与缺血性脑卒中患者血管狭窄部位无明显关系。
[Abstract]:Objective: to investigate the relationship between H type hypertension and ischemic stroke vascular stenosis. Methods: 365 patients with ischemic stroke vascular stenosis were selected from Department of Neurology, the first affiliated Hospital of Zhengzhou University. According to the degree of vascular stenosis, they were divided into three groups: mild stenosis, moderate stenosis and severe stenosis. Blood pressure and serum homocysteine level were measured at the same time. Results: there was a significant correlation between the degree of vascular stenosis in hypertension and ischemic stroke, and the difference was statistically significant (P 0.05). The homocysteine level was compared among different degree of vascular stenosis. There is a significant difference between hypertension and hyperhomocysteinemia. There is no significant correlation between hypertension and hyperhomocysteinemia. Conclusion: there is no significant correlation between hypertension and vascular stenosis. Conclusion: hypertension, hyperhomocysteinemia, hyperhomocysteinemia and hyperhomocysteinemia have no significant correlation with blood vessel stenosis. Homocysteine was an independent risk factor for vascular stenosis, and with the increase of blood pressure and homocysteine, the degree of stenosis increased gradually. There was no significant relationship between hypertension and hyperhomocysteinemia.
【作者单位】：郑州大学第一附属医院神经内科;
【分类号】：R743.3

【参考文献】