联合应用DWI及PWI对脑内肿瘤及瘤周水肿的比较研究

发布时间：2018-03-20 20:52

本文选题：低级别胶质瘤　切入点：高级别胶质瘤　出处：《临床放射学杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的应用DWI及PWI的各项相关参数对低级别胶质瘤、高级别胶质瘤、淋巴瘤及转移瘤的生长趋势,血管生成及瘤周侵犯的情况进行评价。方法应用DWI及PWI检查脑内占位病例54例。分别以肿瘤瘤体实质、肿瘤外水肿内1 cm、肿瘤外水肿内2 cm、水肿外1 cm、水肿区域以外1 cm的白质区域为感兴趣区,以正常脑白质为对照感兴趣区,分别测量各个感兴趣区的ADC、rCBV、rCBF值。将感兴趣区与对照感兴趣区的量化指标进行比值计算,得到相对ADC、相对r CBV、相对rCBF值。并对各项参数进行统计分析。结果不同肿瘤实质ADC值之间(P=0.003)以及瘤周水肿内2 cm处ADC值之间差异具有统计学意义(P=0.012)。HGG瘤体、水肿内1 cm处、水肿内2 cm处的rCBV、rrCBV、rCBF及rrCBF值均高于其他类型肿瘤,差异均存在统计学意义(P0.05)。结论通过DWI及PWI对低级别胶质瘤、高级别胶质瘤、淋巴瘤及转移瘤这四种类型的瘤体、瘤周水肿区、水肿外区域的ADC、rCBV、rCBF值及其相对值的分析,能提高肿瘤的诊断准确率并指导临床手术切除范围。
[Abstract]:Objective to study the growth trend of low grade glioma, high grade glioma, lymphoma and metastasis by DWI and PWI. Methods DWI and PWI were used to examine 54 cases of brain mass. The area of interest was 1 cm in the outer edema, 2 cm in the external edema, 1 cm outside the edema area, and 1 cm outside the edema area. The normal white matter was used as the control area of interest. The values of ADCrCBV and rCBF of each region of interest were measured, and the quantitative indexes of the region of interest and the control region of interest were calculated. The relative ADC value, relative rCBV value and relative rCBF value were obtained. The results showed that there were significant differences between the ADC values of different tumor parenchyma and the ADC values of 2 cm in peri-tumor edema, 1 cm in edema, and 1 cm in edema. The values of rCBV, rrCBV, rCBF and rrCBF in 2 cm of edema were higher than those in other types of tumors, and the differences were statistically significant (P 0.05). Conclusion DWI and PWI can be used to treat four types of tumors, including low grade glioma, high grade glioma, lymphoma and metastatic tumor, and the edema area around the tumor. The analysis of the rCBF value and the relative value of ADCC rCBV in the extraedema area can improve the diagnostic accuracy of tumor and guide the scope of clinical surgical resection.
【作者单位】：江西省赣州市人民医院影像科;
【分类号】：R445.2;R739.4

【相似文献】