MOCA量表和MMSE在帕金森病轻度认知功能障碍筛查中的应用

发布时间：2018-03-21 13:25

本文选题：蒙特利尔认知评估量表　切入点：简易精神状态量表　出处：《昆明医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的：探讨蒙特利尔认知评估量表(Montreal Cognitive Assessment,MOCA)和简易精神状态量表(Mini-Mental state examina, MMSE)在帕金森病轻度认知功能障碍(Parkinson disease with mild cognitive impairment, PDMCI)筛查中的应用方法：所有样本采用随机抽样方法,应用MOCA和MMSE对75例诊断为PDMCI患者、帕金森病认知功能正常(Parkinson disease with normal cognition, PDN)患者180例和健康患者145例进行评估,比较二者筛查PDMCI的敏感性和特异性。结果：在文盲组MMSE的敏感性为93.1%,特异性为100%,而MOCA的敏感性仅为0%,特异性为92.7%；在小学组MMSE的敏感性为87.5%, 特异性为100%,而MOCA的敏感性为41.67%,特异性为79.2%：在初中及以上学历组MMSE的敏感性为27.3%,特异性为100%,MOCA的敏感性为90.9%,特异性为85,7%。结论：MOCA在初中以上学历为高敏感性的PDMCI筛查工具,MMSE适合初中以下学历PD MCI筛查工具。
[Abstract]:Objective: to investigate the application of Montreal Cognitive Assessment scale (MOCA) and Mini-Mental state examination (MMSEMA) in the screening of Parkinson disease with mild cognitive impairment (PDMCs) with mild cognitive impairment in Parkinson's disease. Methods: 75 patients with PDMCI, 180 patients with normal Parkinson disease with normal cognition (PDNs) and 145 healthy controls were assessed by MOCA and MMSE. The sensitivity and specificity of PDMCI screening were compared. Results: in the illiterate group, the sensitivity of MMSE was 93.1 and the specificity was 100, while the sensitivity of MOCA was only 0 and the specificity was 92.7.The sensitivity of MMSE in primary school was 87.5. The specificity was 100, while the sensitivity of MOCA was 41.67 and the specificity was 79.2: in junior high school and above, the sensitivity of MMSE was 27.3, the specificity of 100g was 90.9 and the specificity was 85. 7. Conclusion MMSE is a highly sensitive PDMCI screening tool for junior high school and above junior high school. It is suitable for PDMCI screening under junior high school.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R742.5

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