糖尿病与应激性高血糖对急性脑梗死患者预后影响研究

发布时间：2018-03-23 19:12

本文选题：脑梗死　切入点：糖尿病　出处：《中国全科医学》2017年S2期

【摘要】：目的探讨糖尿病与应激性高血糖对急性脑梗死(ACI)患者预后的影响。方法选择2013年2月—2016年2月广东省五华县人民医院住院治疗的ACI患者120例,依据患者病史及入院后血糖水平的变化分为糖尿病组、应激性高血糖组和正常血糖组,每组各40例。记录3组患者就诊时、治疗10 d后、治疗30 d后与治疗60 d后神经功能缺损评分(NIHSS)和Barthel指数,并统计3组患者的病死率。结果就诊时3组患者NIHSS评分、Barthel指数比较,差异无统计学意义(P0.05);治疗10、30、60 d后3组患者NIHSS评分、Barthel指数比较,差异均有统计学意义(P0.05);治疗10、30、60 d后,糖尿病组和应激性高血糖组NIHSS评分高于正常血糖组,Barthel指数低于正常血糖组,差异均有统计学意义(P0.05)。治疗60 d后糖尿病组和应激性高血糖组患者病死率高于正常血糖组,差异有统计学意义(P0.01)。结论对于伴有糖尿病或应激性高血糖ACI患者,应积极控制患者的血糖,对提高临床疗效与改善患者预后具有重要的临床意义。
[Abstract]:Objective to investigate the effect of diabetes mellitus and stress hyperglycemia on the prognosis of patients with acute cerebral infarction (ACI). Methods 120 ACI patients hospitalized in Wuhua people's Hospital of Guangdong Province from February 2013 to February 2016 were selected. According to the history of the patients and the changes of blood glucose after admission, they were divided into three groups: diabetic group, stress hyperglycemia group and normal blood glucose group, with 40 cases in each group. After 30 days of treatment and 60 days after treatment, the neurological impairment scores (NIHSS) and Barthel index were compared, and the fatality rate of the three groups was calculated. Results the NIHSS scores and the Barthel index of the three groups were compared at the time of treatment. There was no significant difference in NIHSS scores between the three groups after treatment for 10 ~ 30 ~ 60 days (P 0.05), and the NIHSS scores in diabetic group and stress hyperglycemia group were significantly higher than those in normal blood glucose group after 60 days of treatment (P < 0. 05), and the NIHSS scores in diabetic group and stress hyperglycemia group were significantly lower than those in normal blood glucose group (P < 0. 05). The mortality of diabetes mellitus and stress hyperglycemia group was higher than that of normal blood glucose group after 60 days treatment, and the difference was statistically significant (P 0.01). Conclusion the mortality of patients with diabetes mellitus or stress hyperglycemia ACI is significantly higher than that of normal blood glucose group. It is of great clinical significance to control the blood sugar actively and to improve the clinical effect and prognosis of the patients.
【作者单位】：广东省五华县人民医院内一科;广东省梅州市人民医院神经内科;
【分类号】：R587.1;R743.33

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