磁共振平均相对脑血容量鉴别胶质瘤复发与放射损伤诊断准确性的Meta分析

发布时间：2018-03-24 02:25

本文选题：神经胶质瘤　切入点：脑损伤　出处：《磁共振成像》2016年03期

【摘要】：目的评价磁共振平均相对脑血容量(rCBVmean)鉴别胶质瘤复发与放射损伤的诊断准确性。材料与方法系统性检索2000年1月至2015年8月Pubmed、Embase和CBM数据库中发表的有关磁共振rCBVmean鉴别胶质瘤复发与放射性损伤的文献。对纳入的文献进行质量评价及数据提取,应用Stata13.0软件进行Meta分析。结果共纳入14篇符合标准的文献,包括378例患者,合并敏感性(SEN)、特异性(SPE)、阳性似然比(PLR)、阴性似然比(NLR)和诊断优势比(DOR)分别为0.87(95%CI:0.80~0.91),0.89(95%CI:0.81~0.94),7.6(95%CI:4.3~13.4),0.15(95%CI:0.10~0.23)和50(95%CI:22~117)。综合受试者工作特性曲线(SROC)下面积为0.93(95%CI:0.91~0.95)。结论磁共振r CBVmean在鉴别胶质瘤复发与放射性损伤中具有高的诊断准确性。
[Abstract]:Objective to evaluate the diagnostic accuracy of MRI mean relative cerebral blood volume (RCBV mean) in the differential diagnosis of glioma recurrence and radiation injury. Materials and methods A systematic search of the relevant MRI rCBVmean published in Pubmedme Embase and CBM databases from January 2000 to August 2015 was carried out. The literature of differentiating glioma recurrence from radiation injury. The quality evaluation and data extraction of the included documents were carried out. Meta analysis was performed with Stata13.0 software. Results A total of 14 articles, including 378 patients, were included. The combined sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 0.8795% and 0.8995% respectively. Conclusion the area of r CBVmean in differentiating glioma from recurrence is 0.910.95. Conclusion the area of r CBVmean is 0.931 ~ 0 95. Conclusion the area of r CBVmean in differentiating glioma from radiation is 0.931 ~ 0.950.Conclusion the area under the operating characteristic curve of the subjects is 0.9395CI0 / 0.910.95. Conclusion the area of r CBVmean is 0.9395CI0.910.Conclusion the area under the operating characteristic curve of the subjects is 0.9395CI0.910.Conclusion\\\%\%\%\%\% of glioma and radiation\%\%\%\%\%\%\%\%\%\%\%\%\%\%\%\%\%? The diagnosis accuracy of sexual injury is high.
【作者单位】：天津医科大学研究生院;北京武警总医院磁共振科;天津市环湖医院磁共振科;天津市环湖医院放疗科;
【基金】：天津市卫生局公关项目(编号:12KG113)
【分类号】：R445.2;R739.41

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