复元醒脑与活血通腑治疗急性脑出血临床对照研究

发布时间：2018-04-19 22:00

本文选题：复元醒脑 + 活血通腑　；参考：《成都中医药大学》2014年博士论文

【摘要】：目的：评价元气亏虚贯穿在急性脑出血的整个过程,比较复元醒脑法与活血通腑在急性脑出血的临床疗效。方法：在全国5家医疗单位开展复元醒脑与活血通腑治疗急性脑出血临床对照研究,治疗组采用复元醒脑法方案,即在常规西医治疗基础上,加用具有益气活血、泄热熄风功效的中风醒脑方(红参、大黄、川芎、三七)；对照组采用活血通腑法方案,采用常规西医治疗基础上加大黄、川芎、三七。观察患者治疗前后神经功能缺损积分、血肿吸收率、中医症状体征严重程度积分、电解质紊乱肺部感染、便秘等指标的改变,评价治疗14±2天、21±3天患者的情况。结果： 1.神经功能缺损改变：治疗14±2天、21±3天治疗神经功能缺损积分改善情况优于对照组,差异有统计学意义(P0.05)； 2.血肿吸收率：14±2天时治疗组血肿吸收率优于对照组,差异有统计学意义(P0.05)； 3.中医症状体征改变：治疗14±2天、21±3天治疗组中医症状体征积分改善情况优于对照组,差异有统计学意义(P0.05)； 4.治疗组肺部感染改善情况优于对照组,差异有统计学意义(P0.01) 5.治疗组电解质紊乱改善情况优于对照组,差异有统计学意义(P0.01) 6.便秘情况：治疗组便秘改善情况优于对照组,差异有统计学意义(P0.05) 结论： 1.复元醒脑法治疗方案能改善急性脑出血患者神经功能缺损情况,在治疗21±3天时改善患者的神经功能缺损程度优于活血通腑法治疗方案； 2.复元醒脑法治疗方案能促进出急性脑出血患者血肿吸收,在14±2天时优于活血通腑法治疗方案； 3.复元醒脑法治疗方案在改善症状体征的严重程度积分及对生活的影响程度上优于活血通腑法治疗方案。 4.复元醒脑法治疗方案在改善肺部感染情况上优于活血通腑法治疗方案。 5.复元醒脑法治疗方案在改善电解质紊乱情况上优于活血通腑法治疗方案。 6.复元醒脑法治疗方案在改善便秘情况优于活血通腑法治疗方案。
[Abstract]:Objective: to evaluate the clinical efficacy of Fuyuan Xingnao method and Huoxue Tongfu in acute intracerebral hemorrhage. Methods: a clinical controlled study on the treatment of acute cerebral hemorrhage was carried out in 5 medical units in China. In the treatment group, the treatment group was treated with Fuyuan Xingnao method, that is, on the basis of routine western medicine treatment, the treatment group was treated with a combination of nourishing qi and activating blood circulation. Xingnao Fang of apoplexy (Radix Ginseng, Rhubarb, Chuanxiong, Panax Notoginseng, Radix et Rhizoma et Rhizoma Chuanxiong, Panax notoginseng). The changes of neurological deficit score, hematoma absorption rate, severity score of symptoms and signs of TCM, electrolyte disturbance pulmonary infection and constipation were observed before and after treatment, and the results of 14 卤2 days and 21 卤3 days of treatment were evaluated. Results: 1. The improvement of neural function defect score in 14 卤2 days and 21 卤3 days of treatment was better than that in the control group, and the difference was statistically significant (P 0.05). 2. The hematoma absorption rate in the treatment group was better than that in the control group on the day of 14 卤2 days, and the difference was statistically significant (P 0.05). 3. The changes of TCM symptoms and signs: the improvement of TCM symptom and sign score in the treatment group was better than that in the control group on 14 卤2 days and 21 卤3 days, and the difference was statistically significant (P 0.05); 4. The improvement of pulmonary infection in the treatment group was better than that in the control group (P 0.01). 5. The improvement of electrolyte disturbance in the treatment group was better than that in the control group (P 0.01). 6. Constipation: the improvement of constipation in the treatment group was better than that in the control group (P 0.05). Conclusion: 1. Fuyuan Xingnao method can improve the neurological function defect in patients with acute intracerebral hemorrhage, and it is better than Huoxue Tongfu method in improving the degree of neurological function defect in 21 卤3 days. 2. Fuyuan Xingnao method can promote hematoma absorption in patients with acute intracerebral hemorrhage, and it is better than Huoxue Tongfu method in 14 卤2 days. 3. Fuyuan Xingnao method was superior to Huoxue Tongfu method in improving the severity score of symptoms and signs and its influence on life. 4. Fuyuan Xingnao method is superior to Huoxue Tongfu method in improving pulmonary infection. 5. Fuyuan Xingnao method is superior to Huoxue Tongfu method in improving electrolyte disorder. 6. Fuyuan Xingnao method is better than Huoxue Tongfu method in improving constipation.
【学位授予单位】：成都中医药大学
【学位级别】：博士
【学位授予年份】：2014
【分类号】：R743.3

【参考文献】