尤瑞克林联合降纤酶对急性脑梗塞患者的神经功能缺损及血浆纤维蛋白原的影响

发布时间：2018-04-27 23:29

本文选题：尤瑞克林 + 降纤酶　；参考：《中国地方病防治杂志》2017年01期

【摘要】：目的探讨尤瑞克林联合降纤酶对急性脑梗塞患者神经功能缺损及血浆纤维蛋白原的影响。方法 67例急性脑梗塞患者随机分为对照组33例,观察组34例,对照组予尤瑞克林治疗,观察组予尤瑞克林联合降纤酶治疗,比较两组治疗前后神经功能缺损(NIHSS)评分、血浆纤维蛋白原水平,统计临床疗效及不良反应发生率。结果观察组总有效率94.12%高于对照组72.73%(P0.05);治疗后1、2周、1个月观察组NIHSS评分及血浆纤维蛋白原水平均低于对照组(P0.05);两组不良反应发生率差异无统计学意义(P0.05)。结论尤瑞克林联合降纤酶治疗急性脑梗塞患者疗效显著,可有效改善患者血浆纤维蛋白原水平及神经功能缺损程度,安全性高。
[Abstract]:Objective to investigate the effects of eurexine combined with defibrase on neurologic impairment and plasma fibrinogen in patients with acute cerebral infarction. Methods Sixty-seven patients with acute cerebral infarction were randomly divided into control group (n = 33) and control group (n = 34). Plasma fibrinogen level, clinical efficacy and incidence of adverse reactions were counted. Results the total effective rate in the observation group was 94.12% higher than that in the control group (72.73), the NIHSS score and plasma fibrinogen level in the observation group were lower than those in the control group at 1 week and 1 month after treatment, and there was no significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion Urethrin combined with defibrase is effective in the treatment of acute cerebral infarction. It can effectively improve the plasma fibrinogen level and the degree of nerve function defect in patients with acute cerebral infarction.
【作者单位】：郑州大学第五附属医院神经内科;
【基金】：国家自然科学基金资助项目(面上项目)(编号:81571137)
【分类号】：R743.33

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