颈动脉超声联合相关检验指标检测在诊断脑梗死中的价值

发布时间：2018-04-28 23:35

本文选题：颈动脉超声 + 脑梗死　；参考：《贵州医药》2016年11期

【摘要】：目的评价颈动脉超声联合同型半胱氨酸、糖化血红蛋白以及血脂水平在诊断脑梗死中的价值。方法脑梗死患者100例(实验组),按照病史及血糖检测继续分为糖尿病组、高血糖组以及正常血糖组,同期体检健康人员60例(对照组),颈动脉彩超检测实验组及对照组人员颈动脉内中膜厚度以及全自动生化分析仪检测外周血中同型半胱氨酸、糖化血红蛋白、血脂相关指标水平。结果实验组检测出70例颈动脉不同程度的内中膜增厚,发生率为70%(χ2=54.1,P0.001);实验组的HCY,HbA1c,TC,TG,LDL均高于正常对照组,而HDL低于正常对照组(t=6.25,10.6,13.6,6.3,5.39,-4.2;P均0.005);实验组中颈动脉内中膜厚度明显增高(t=12.3,P0.001);糖尿病组与高血糖组的糖化血红蛋白均高于正常血糖组(t=-13.4~-10.7,P均0.005),并且糖尿病组与高血糖组颈动脉彩超显示颈动脉内中膜厚度要明显高于正常血糖组(t=-8.98~-2.88,P均0.005)。结论脑梗死的发病率与颈动脉粥样硬化密切相关;糖化血红蛋白水平与脑梗死的病情程度密切相关,可以作为判断病情的有效指标;颈动脉彩超联合脑卒中相关指标检测可以提高脑梗死的检出率。
[Abstract]:Objective to evaluate the value of carotid ultrasound combined with homocysteine, glycosylated hemoglobin and serum lipids in the diagnosis of cerebral infarction. Methods 100 patients with cerebral infarction (experimental group) were divided into diabetic group, hyperglycemia group and normal blood glucose group according to their history and blood glucose test. In the same period, 60 healthy persons (control group, carotid artery color Doppler ultrasound, carotid artery intima media thickness and automatic biochemical analyzer were used to detect homocysteine and glycosylated hemoglobin in peripheral blood. Serum lipids related index level. Results 70 cases of carotid artery thickening were detected in the experimental group, the incidence was 70 (蠂 2 / 54.1 / P 0.001), and the levels of HCYN HbA1 / TCU TGG / LDL in the experimental group were significantly higher than those in the control group (P < 0. 05). HDL was significantly lower than that in the normal control group (P 0.005), the thickness of carotid intima was significantly higher in the experimental group than that in the control group, and the glycosylated hemoglobin levels in the diabetic group and hyperglycemia group were higher than those in the normal blood glucose group (t -13.4- 10.7g P 0.005), and the carotid artery thickness in the diabetic group and the hyperglycemia group was significantly higher than that in the diabetic group and the hyperglycemia group (P = 0.005), while in the diabetic group and the hyperglycemia group, the level of glycosylated hemoglobin was significantly higher than that in the control group. The intima media thickness of carotid artery was significantly higher than that of normal blood glucose group (P 0.005). Conclusion the incidence of cerebral infarction is closely related to carotid atherosclerosis, and the level of glycosylated hemoglobin is closely related to the severity of cerebral infarction. Carotid ultrasound combined with stroke related indexes can improve the detection rate of cerebral infarction.
【作者单位】：十堰市太和医院/湖北医药学院附属太和医院妇产科;贵州省肿瘤医院妇瘤外科;十堰市太和医院/湖北医药学院附属太和医院检验科;
【基金】：国家自然科学基金(21470245) 湖北省自然科学杰出青年项目(2015CFA030) 湖北省卫生与计划生育委员会青年基金项目(WJ2015Q039) 太和医院重点项目(2014JJXM019)
【分类号】：R445.1;R743.33

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