丹红注射液联合奥拉西坦治疗脑梗塞的疗效分析

发布时间：2018-04-29 18:47

  本文选题：脑梗塞 + 丹红注射液　； 参考：《西部医学》2016年02期

【摘要】：目的探讨丹红注射液联合奥拉西坦治疗脑梗塞的疗效;方法将我院收治的76例脑梗塞患者随机分为对照组与治疗组,分别以丹红注射液(对照组)及丹红注射液联合奥拉西坦(治疗组)进行静脉滴注,对比两组的临床疗效及治疗前后的神经功能缺损程度与血液流变学指标。结果治疗组的有效率97.3%,对照组有效率为92.2%,但未见显著差异。而治疗组的治愈率、显效率均显著高于对照组(P0.05);治疗3个月后,治疗组的NIM评分与治疗前对比有了显著下降(P0.05);而对照组虽有下降,但差异无统计学意义(P0.05),其评分高于治疗组(P0.05);治疗后,所有患者的全血浆粘度、血小板聚集率、血栓形成系数及心排血指数均相对治疗前有了显著下降(P0.05),但治疗组的下降程度更低于对照组(P0.05),并且对于两组患者治疗后脑部血液动力学指标如:平均血流量、平均血流速度、脑血管特性阻抗均在治疗后明显上升,差异有统计学意义(P0.05);脑血管外周阻力变化显著,差异有统计学意义(P0.01)。结论丹红注射液联合奥拉西坦可促进脑梗塞的临床治疗效果,促进神经功能的恢复,有效改善患者预后。
[Abstract]:Objective to investigate the therapeutic effect of Danhong injection combined with oxiracetam on cerebral infarction methods 76 patients with cerebral infarction in our hospital were randomly divided into control group and treatment group. Danhong injection (control group) and Danhong injection combined with oxiracetam (treatment group) were given intravenously respectively. The clinical efficacy, the degree of nerve function defect and hemorheology were compared between the two groups before and after treatment. Results the effective rate of the treatment group was 97.3%, while the control group was 92.2%, but there was no significant difference. After 3 months of treatment, the NIM score of the treatment group was significantly lower than that of the pre-treatment group (P 0.05), while the control group had a decrease. But the difference was not statistically significant (P 0.05), and its score was higher than that in the treatment group (P 0.05). After treatment, the whole plasma viscosity and platelet aggregation rate of all patients were higher than those of the treatment group. The thrombus formation coefficient and cardiac blood excretion index were significantly decreased compared with those before treatment, but the degree of decrease in the treatment group was lower than that in the control group (P 0.05), and the cerebral hemodynamic indexes such as mean blood flow, mean blood flow velocity after treatment in both groups were lower than those in the control group. The characteristic impedance of cerebrovascular increased significantly after treatment, the difference was statistically significant (P 0.05), and the change of peripheral resistance was significant (P 0.01). Conclusion Danhong injection combined with olaxetam can promote the clinical effect of cerebral infarction, promote the recovery of nerve function and improve the prognosis of the patients.
【作者单位】： 武汉市东西湖区人民医院神经内科;珠海市第二人民医院检验科;
【基金】：湖北省科技支撑项目(hb2012D136001342)
【分类号】：R743.3
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本文编号：1821132