介入再通术改善慢性闭塞性脑血管病变患者认知功能的初步研究

发布时间：2018-05-04 00:07

本文选题：介入再通术 + 慢性闭塞性脑血管病　；参考：《第三军医大学学报》2017年06期

【摘要】：目的观察介入再通术对慢性闭塞性脑血管病变(chronic total cerebrovascular occlusion,CTO)患者认知功能的改善情况,并与未进行血管再通的CTO患者进行对比。方法选择我院2013年5月至2016年5月收治的CTO患者55例,其中介入再通组(治疗组)21例,非再通组(对照组)34例,比较术后12、24个月认知功能情况,采用简易智能精神状态检查量表(mini-mental state examination,MMSE)、蒙特利尔认知功能评分表(Montreal cognitive assessment,Mo CA)评估患者认知功能。结果治疗组与对照组患者术前美国国立卫生研究院卒中评分量表(national institute of health stroke scale,NIHSS)评分差异有统计学意义(P0.05),而性别、年龄、文化程度、脑血管危险因素、认知功能等基线资料差异没有统计学意义(P0.05)。随访期间,两组患者认知功能(12个月后MMSE、Mo CA,24个月后MMSE、Mo CA量表评分)比较差异有统计学意义(P0.05,P0.01)。结论介入再通术可以明显改善CTO患者的认知功能。
[Abstract]:Objective to observe the improvement of cognitive function in patients with chronic total cerebrovascular inclusion (CTO) by interventional recanalization, and to compare it with CTO patients without revascularization. Methods 55 patients with CTO were selected from May 2013 to May 2016 in our hospital, including 21 patients in the interventional recanalization group and 34 patients in the non-recanalization group. The cognitive function was compared at 12 and 24 months after operation. The mini-mental state examination and Montreal cognitive assessment were used to evaluate the cognitive function of the patients. Results the scores of national institute of health stroke scale were significantly different between the treatment group and the control group before operation (P 0.05), but gender, age, education level, cerebrovascular risk factors were significantly different between the treatment group and the control group. There was no significant difference in baseline data such as cognitive function (P 0.05). During the follow-up period, there were significant differences in cognitive function between the two groups (MMSE Mo CA after 12 months and MMSE Mo CA score 24 months later). Conclusion Interventional recanalization can significantly improve the cognitive function of CTO patients.
【作者单位】：第三军医大学西南医院神经内科;第三军医大学西南医院心理科;
【分类号】：R743

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