新疆地区缺血性脑卒中患者颅外段脑血管支架治疗长期随访分析

发布时间：2018-05-08 08:40

本文选题：颅外段脑血管 + 支架　；参考：《中国动脉硬化杂志》2017年03期

【摘要】：目的评价新疆地区颅外段脑动脉狭窄患者颈动脉血管支架置入术(CAS)和椎动脉起始端支架置入术(VAOS)治疗的安全性和有效性。方法颅外段颈动脉狭窄或椎动脉起始部狭窄患者323例,回顾性分析其CAS和VAOS术前和术后随访记录,分析支架置入成功率、围术期并发症,及随访期间支架置入后再狭窄率和临床终点事件的发生率。结果 CAS和VAOS组手术成功率为100%,围手术期并发症发生率分别为14.4%和1.2%,随访期间临床终点事件的发生率分别为15.1%和12.8%,再狭窄的发生率为8.8%和13.4%,Cox回归分析发现在CAS组中,男性和多支血管病变为发生再狭窄的危险因素(HR=19.249,P=0.02;HR=0.069,P=0.034);VAOS组中,对侧椎动脉狭窄为发生再狭窄的危险因素(HR=0.075,P=0.001)。结论 CAS和VAOS治疗颅外段动脉狭窄相对安全,但应重视术中及术后并发症的预防及处理。
[Abstract]:Objective to evaluate the safety and efficacy of carotid artery stenting (CAS) and vertebral artery initial stenting (VAOS) in patients with extracranial cerebral artery stenosis in Xinjiang. Methods 323 patients with extracranial carotid artery stenosis or vertebral artery stenosis were retrospectively analyzed before and after CAS and VAOS. The success rate of stent implantation and perioperative complications were analyzed. The rate of restenosis and the incidence of clinical endpoint events after stent implantation. Results in CAS and VAOS groups, the successful rate of operation was 100%, the incidence of perioperative complications was 14.4% and 1.2%, the incidence of clinical endpoint events was 15.1% and 12.8%, and the incidence of restenosis was 8.8% and 13.4Cox regression analysis in CAS group. Male and multivessel lesions were risk factors for restenosis. In the VAOS group, the contralateral vertebral artery stenosis was a risk factor of restenosis. Conclusion CAS and VAOS are relatively safe in the treatment of extracranial artery stenosis, but we should pay attention to the prevention and management of complications during and after operation.
【作者单位】：新疆医科大学第一附属医院神经内科;
【分类号】：R743.3

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