芪参归汤联合丁苯酞注射液治疗脑梗死的临床观察

发布时间：2018-05-09 05:14

  本文选题：脑梗死 + 治疗　； 参考：《中华中医药学刊》2017年06期

【摘要】：目的:观察芪参归汤联合丁苯酞注射液治疗脑梗死的临床疗效。方法:将106例脑梗死患者随机分为治疗组和对照组各53例,两组患者均采用常规基础治疗方法,对照组在常规治疗基础上加用丁苯酞氯化钠注射液,100 m L/次,每日2次;治疗组在对照组治疗基础上加用芪参归汤水煎剂,每次200 m L,早晚分两次服用。两组均治疗2周。比较两组神经功能缺损恢复情况,临床疗效,肿瘤坏死因子α(TNF-α)、神经元特异性烯醇化酶(NSE)、全血黏度、血浆黏度指标水平,以及不良反应情况。结果:治疗组神经功能缺损恢复优于对照组(P0.05);治疗组患者临床疗效优于对照组(P0.05);治疗组患者肿瘤坏死因子α(TNF-α)、神经元特异性烯醇化酶(NSE)、全血黏度、血浆黏度改善较对照组更明显(P0.05);而比较两组治疗后均无不良反应发生。结论:芪参归汤联合丁苯酞注射液治疗脑梗死,临床疗效确切,神经功能缺损恢复明显,安全可靠,值得临床推广。
[Abstract]:Objective: to observe the clinical effect of Qishen Gui decoction combined with butyphthalide injection in the treatment of cerebral infarction. Methods: 106 patients with cerebral infarction were randomly divided into treatment group (n = 53) and control group (n = 53). The treatment group in the control group on the basis of treatment plus Qishen Gui decoction decoction, 200 mL each time, morning and evening were taken twice. Both groups were treated for 2 weeks. The recovery of nerve function defect, clinical effect, TNF- 伪, neuron-specific enolase (NSEE), whole blood viscosity, plasma viscosity, and adverse reactions were compared between the two groups. Results: the recovery of nerve function defect in the treatment group was better than that in the control group (P 0.05), the clinical effect in the treatment group was better than that in the control group (P 0.05), the tumor necrosis factor 伪 -titran (TNF- 伪), neuron specific enolase (NSEE) and whole blood viscosity in the treatment group were better than those in the control group. The improvement of plasma viscosity was more obvious than that of control group (P 0.05), but there was no adverse reaction after treatment in both groups. Conclusion: Qishen Gui decoction combined with butyphthalide injection in the treatment of cerebral infarction has definite clinical effect, obvious recovery of nerve function defect, safety and reliability, and is worth popularizing in clinic.
【作者单位】： 舟山市中医院心血管脑病科;
【基金】：浙江省中医药科学研究基金项目(2014ZSZX05)
【分类号】：R743.3
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本文编号：1864732