甘油果糖联合吡拉西坦治疗糖尿病脑出血后脑水肿效果观察

发布时间：2018-06-04 01:51

本文选题：甘油果糖 + 吡拉西坦　；参考：《中国乡村医药》2016年23期

【摘要】：目的观察甘油果糖联合吡拉西坦治疗2型糖尿病脑出血后脑水肿的效果。方法该院收治的2型糖尿病脑出血后脑水肿患者70例,按入院时间分为吡拉西坦组与联合组各35例。两组均予常规治疗,联合组采用甘油果糖联合吡拉西坦治疗,吡拉西坦组仅采用吡拉西坦治疗,两个疗程后观察疗效。结果联合组脑水肿体积、神经功能缺损程度(NIHSS)评分及丙二醛(MDA)水平低于吡拉西坦组,日常生活能力Barthel指数(BI)评分及血清超氧化物歧化酶(SOD)水平高于吡拉西坦组,差异均有统计学意义。两组均未见严重药物不良反应。结论甘油果糖联合吡拉西坦治疗糖尿病脑出血后脑水肿效果优于单用吡拉西坦治疗。
[Abstract]:Objective to observe the effect of fructose combined with Piracetam on cerebral edema after type 2 diabetic intracerebral hemorrhage. Methods 70 patients with cerebral edema after type 2 diabetic intracerebral hemorrhage were divided into two groups: Piracetam group (35 cases) and combined group (35 cases). Both groups were treated with routine therapy. The combined group was treated with fructose combined with Piracetam, and the group with Piracetam was treated only with Piracetam. The curative effect was observed after two courses of treatment. Results the scores of brain edema volume, neurological impairment and malondialdehyde (MDA) in the combined group were lower than those in the Piracetam group, and the scores of Barthel index and serum superoxide dismutase (SOD) were higher in the combined group than in the Piracetam group. The difference was statistically significant. There were no serious adverse drug reactions in both groups. Conclusion Glycerol fructose combined with Piracetam is more effective than Piracetam in the treatment of cerebral edema after diabetic intracerebral hemorrhage.
【作者单位】：浙江永康市第一人民医院神经内科;
【分类号】：R587.2;R743.34

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