脑侧支循环建立对急性期脑梗死患者预后的影响

发布时间：2018-06-09 15:43

本文选题：急性期脑梗死 + 侧支循环　；参考：《广东医学院学报》2016年06期

【摘要】：目的探讨急性期脑梗死病灶周围是否存在侧支循环以及脑侧支循环对其预后的影响。方法收集符合入组标准患者99例,根据PWI结果分为脑侧支循环建立组(简称侧支组,n=37)和脑灌注不足组(n=62),其中脑灌注不足组又分为尤瑞克林干预组(简称干预组,n=38)与非尤瑞克林干预组(简称非干预组,n=24)。侧支组与非干预组均按脑梗死常规处理;干预组则予脑梗死常规处理+尤瑞克林。所有入选患者均在入院时进行NIHSS评分,于分组后第10天评定疗效,3个月后用m RS评分评估预后。结果 (1)治疗前,侧支组的rCBV、rCBF值均大于灌注不足组(P0.01),MTT则差异无统计学意义(P0.05)。(2)侧支组患者的疗效和预后均优于脑灌注不足组及非干预组(P0.05或0.01),与干预组比较则差异无统计学意义(P0.05);尤瑞克林干预组的疗效与预后均优于非干预组(P0.05或0.01)。结论急性期脑梗死病灶周围存在侧支循环;脑侧支循环建立的脑梗死患者预后比未建立脑侧支循环者预后好。
[Abstract]:Objective to investigate the existence of collateral circulation around the focus of acute cerebral infarction and the influence of collateral circulation on the prognosis. Methods 99 patients who met the standard of admission were collected. According to the results of PWI, the patients were divided into two groups: the lateral collateral circulation establishment group (NJ 37) and the cerebral perfusion insufficiency group (NJ 62). Among them, the cerebral perfusion deficiency group was divided into two groups: Urikline intervention group (Eucrine intervention group) and non eucrine intervention group (non eurethrin intervention group), and the brain perfusion deficiency group was divided into two groups: Urikline intervention group and non eucrine intervention group. The lateral branch group and non-intervention group were treated according to the routine treatment of cerebral infarction, and the intervention group were treated with the routine treatment of eucrine. All the patients were evaluated with NIHSS on admission, the curative effect was evaluated on the 10th day after the grouping, and the prognosis was evaluated by Mrs after 3 months. Results 1) before treatment, The rCBVV rCBF value in the collateral group was higher than that in the perfusion deficiency group (P 0.01). There was no significant difference in the efficacy and prognosis of the lateral branch group compared with the cerebral perfusion deficiency group and the non-intervention group (P0.05 or 0.01), but there was no significant difference compared with the intervention group (P0.05). The curative effect and prognosis of Rickering intervention group were better than that of non-intervention group (P 0.05 or 0. 01%). Conclusion there is collateral circulation around the focus of acute cerebral infarction, and the prognosis of patients with cerebral infarction established by cerebral collateral circulation is better than that of patients without cerebral collateral circulation.
【作者单位】：广东省肇庆市第一人民医院神经内科;
【基金】：广东省医学科研基金立项管理项目(No.B2015146) 肇庆市科技创新指导类项目(No.201504030813)
【分类号】：R743.33

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