简化院内救治流程对急性缺血性脑卒中患者静脉溶栓效果的影响

发布时间：2018-06-16 09:25

本文选题：院内救治流程 + 缺血性脑卒中　；参考：《山东医药》2017年07期

【摘要】：目的探讨简化院内救治流程对急性缺血性脑卒中患者静脉溶栓效果的影响。方法选取2014年1月~2015年12月因急性缺血性脑卒中行重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗的72例患者,其中2014年收治的35例患者为对照组,2015年收治的37例患者为观察组。对照组采用传统的院内救治流程,观察组患者采用简化的院内救治流程。比较两组溶栓7 d时NIHSS评分、改良Rankin评分、症状性颅内出血发生率、病死率。结果观察组DNT、发病至溶栓时间、就诊至CT判读时间、就诊至生化报告时间、就诊至心电图时间均短于对照组(P均0.01)。与对照组相比,观察组溶栓7 d时NIHSS评分、改良Rankin评分、症状性颅内出血发生率及病死率显著降低,P均0.05。结论简化院内救治流程可提高急性缺血性脑卒中溶栓治疗的效果。
[Abstract]:Objective to investigate the effect of simplified in-hospital treatment on intravenous thrombolysis in patients with acute ischemic stroke. Methods from January 2014 to December 2015, 72 patients with acute ischemic stroke were treated with recombinant tissue plasminogen activator (rt-PA) intravenous thrombolytic therapy, including 35 patients in 2014 as control group and 37 patients in 2015 as observation group. The patients in the control group were treated with the traditional in-hospital treatment procedure, while the patients in the observation group were treated with the simplified in-hospital treatment procedure. NIHSS score, modified Rankin score, incidence of symptomatic intracranial hemorrhage and mortality were compared between the two groups at 7 days after thrombolysis. Results in the observation group, the time from onset to thrombolysis, from diagnosis to CT interpretation, from visit to biochemical report, and from ECG to the control group were all shorter than those of control group (P < 0.01). Compared with the control group, the NIHSS score, the modified Rankin score, the incidence of symptomatic intracranial hemorrhage and the mortality were significantly decreased in the observation group at 7 days after thrombolysis (P < 0.05). Conclusion simplifying hospital treatment procedure can improve the effect of thrombolytic therapy for acute ischemic stroke.
【作者单位】：华中科技大学同济医学院附属普爱医院;
【基金】：湖北省自然科学基金资助项目(2014CFC1046)
【分类号】：R743.3

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