癫痫患者情绪状态影响因素的分析

发布时间：2018-06-18 05:18

本文选题：癫痫 + 抑郁障碍　；参考：《南昌大学》2014年硕士论文

【摘要】：目的：分析癫痫患者焦虑、抑郁障碍的发生率及影响因素；探讨癫痫与焦虑及抑郁障碍共病的可能发病机制，为癫痫的临床治疗提供理论依据。方法：选择2012年5月~2013年12月在南昌大学二附院神经内科门诊就诊和病房住院的（经知情同意）癫痫患者,严格按照入选标准纳入，采用汉密顿抑郁量表及汉密顿焦虑量表对患者进行测查，用ⅹ2检验及Logistic多元回归分析对相关因素进行分析。结果：癫痫患者抑郁障碍发生率为42.8%，焦虑障碍的发生率为67.9%。单因素卡方检验及多因素Logistic回归分析结果提示：癫痫患者焦虑、抑郁障碍的发生与癫痫的发作类型（OR2.1, P0.820）(OR0.85, P0.098)、发作频率（OR0.34,P0）(OR2.60, P0.011)、病变部位（OR2.08, P0.05）(OR2.10, P0.680)、及文化程度（OR0.64, P0.827）（OR0.70，，P0.593）等因素有关；用药数量(OR1.45, P0.241)是癫痫患者焦虑障碍的影响因素之一,病程(OR0.39, P0.060)是癫痫患者抑郁障碍的影响因素之一;而居住地区（OR0.41，P0.246）可能与癫痫伴发抑郁有关。结论：癫痫患者伴发抑郁、焦虑障碍的主要影响因素是发作频率，癫痫患者伴发抑郁障碍可能的相关因素之一是居住地区。
[Abstract]:Objective: to analyze the incidence and influencing factors of anxiety and depressive disorder in epileptic patients, and to explore the possible pathogenesis of epilepsy with anxiety and depressive disorder in order to provide theoretical basis for the clinical treatment of epilepsy. Methods: patients with epilepsy were selected from May 2012 to December 2013 in the Department of Neurology, second affiliated Hospital, Nanchang University, and hospitalized (with informed consent). Hamilton Depression scale and Hamilton anxiety scale were used to test the patients, and the related factors were analyzed by x 2 test and Logistic multiple regression analysis. Results: the incidence of depressive disorder and anxiety disorder in epileptic patients was 42.8 and 67.9 respectively. The results of univariate chi-square test and multivariate logistic regression analysis showed that the occurrence of anxiety and depression in epileptic patients was related to the type of seizure, such as OR 2.1, P 0.820, OR 0.85, P 0.098, OR 0.34, P 0.011, the site of disease was OR2.08, P0.05OR2.10, P0.680, and the cultural level of OR0.64, P0.827O0.700.593). OR1.45, P0.241) is one of the influencing factors of anxiety disorder in epileptic patients, and the course of disease OR0.39, P0.060) is one of the influencing factors of depressive disorder in epileptic patients, while OR0.41P0.246) may be related to the depression associated with epilepsy. Conclusion: the frequency of seizure is the main influencing factor of depression and anxiety disorder in epileptic patients, and one of the possible related factors of depressive disorder in epileptic patients is residential area.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R742.1

【引证文献】