颈动脉内中膜增厚及斑块对中风和冠心病事件的影响

发布时间：2018-06-20 12:20

本文选题：颈动脉内中膜厚度 + 斑块　；参考：《中国热带医学》2016年01期

【摘要】：目的通过多普勒超声对颈动脉内中膜厚度(IMT)和颈动脉斑块进行检测,探讨IMT、颈动脉斑块对中风和冠心病事件的影响。方法选2015年5月至7月在南京中医药大学附属中西医结合医院心血管内科和神经内科行颈动脉超声的住院患者338例,按IMT是否增厚分IMT增厚组与无IMT增厚组。按颈动脉中是否有斑块分为有斑块组与无斑块组。计算IMT增厚、颈动脉斑块对中风和冠心病发生事件的比值(OR值)。结果 338名患者中235位(69.53%)有IMT增厚,有IMT增厚的患者较无IMT增厚的患者中风事件的发生率增加5.102倍(95%CI,2.858-9.110,P0.01),冠心病事件的发生率增加2.082倍(95%CI,1.221-3.551,P=0.007)。338名患者中215位(63.6%)有颈动脉斑块,有颈动脉斑块的患者较无颈动脉斑块的患者中风事件的发生率增加4.728倍(95%CI,2.793-8.003,P0.01),冠心病事件的发生率增加2.439倍(95%CI,1.462-4.070,P=0.001)。结论心内科和神经内科住院患者颈动脉内中膜增厚及颈动脉斑块的检出率高;IMT增厚对中风事件的影响大于颈动脉斑块,颈动脉斑块对冠心病事件的影响大于IMT增厚。
[Abstract]:Objective to investigate the effects of IMT and carotid plaque on stroke and coronary heart disease by Doppler ultrasound. Methods from May to July 2015, 338 inpatients with carotid artery ultrasound were selected and divided into IMT thickening group and non-IMT thickening group according to whether IMT was thickened or not. According to whether there were plaques in carotid artery, they were divided into plaque group and no plaque group. The ratio of IMT thickening and carotid plaque to events of stroke and coronary heart disease was calculated. Results the incidence of IMT thickening was 5.102 times higher in patients with IMT thickening than in patients without IMT thickening. The incidence of coronary heart disease events was 2.082 times higher than that in patients without IMT thickening. The incidence of coronary heart disease events was 2.082 times higher than that in patients without IMT thickening. The incidence of stroke events in patients with carotid plaques was 4.728 times higher than that in patients without carotid plaques, and the incidence of coronary heart disease events was 2.439 times higher than that of patients without carotid plaques, and the incidence of coronary heart disease events was 2.439 times higher than that of patients without carotid plaques. Conclusion the detection rate of carotid intima-media thickening and carotid plaques in inpatients with cardiology and neurology is higher than that of carotid plaque, and the effect of carotid plaque on coronary heart disease is greater than that of IMT.
【作者单位】：南京中医药大学护理学院;南京中医药大学附属中西医结合医院;杭州市第九中学;
【分类号】：R743.3;R541.4

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