线粒体功能障碍与帕金森病相关性的研究进展

发布时间：2018-06-27 17:31

本文选题：帕金森病 + 线粒体DNA变异　；参考：《继续医学教育》2016年01期

【摘要】：帕金森病(PD)是以中老年人中常见的中枢神经退行性疾病,其病理学过程复杂,近来研究认为线粒体功能障碍与PD形成密切相关,其原因可能为线粒体基因变异、突变以及核基因突变、变异。本文概述了引起线粒体功能障碍的原因及其与PD形成的关系。
[Abstract]:Parkinson's disease (PD) is a common degenerative disease of central nervous system in middle-aged and old people, and its pathological process is complicated. Recent studies have shown that mitochondrial dysfunction is closely related to the formation of PD, which may be caused by mitochondrial gene variation. Mutation and nuclear gene mutation, mutation. This paper summarizes the causes of mitochondrial dysfunction and its relationship with PD formation.
【作者单位】：天津市永久医院神经内科;
【分类号】：R742.5

【共引文献】