高分辨率磁共振评估椎-基底动脉粥样硬化斑块对后循环缺血进展的影响

发布时间：2018-07-15 10:31

【摘要】：目的探讨3.0 T高分辨率磁共振(HR-MRI)评估椎-基底动脉粥样硬化斑块在后循环短暂性脑缺血发作(TIA)病情进展中的价值。方法前瞻性连续纳入2013年7月至2014年7月常熟市第一人民医院神经科门诊及住院的后循环TIA患者30例,均经头部MR血管成像证实存在椎-基底动脉粥样硬化斑块。使用3.0 T HR-MRI对椎-基底动脉斑块进行检查,评估斑块性质及稳定性,根据斑块稳定性结果分为稳定组(16例)与不稳定组(14例)。随访24个月,记录并比较两组患者首次就诊至发生后循环梗死的时间及比例。结果不稳定组发生后循环梗死时间明显短于稳定组,差异有统计学意义[11.5(7.0,20.0)个月比24.0(22.5,24.0)个月,Z=-2.755,P0.05]。稳定组和不稳定组发生后循环梗死的比例分别为5/16、8/14,组间差异无统计学意义(P0.05)。结论应用HR-MRI评估椎-基底动脉粥样硬化斑块结果对后循环缺血疾病的进展有一定参考价值。
[Abstract]:Objective to evaluate the value of 3. 0 T high resolution magnetic resonance imaging (HR-MRI) in the evaluation of vertebrobasilar atherosclerotic plaque in the progression of posterior circulation transient ischemic attack (TIA). Methods from July 2013 to July 2014, 30 patients with posterior circulation TIA were enrolled in the Department of Neurology of the first people's Hospital of Changshu City from July 2013 to July 2014. All patients were confirmed by Mr angiography of their heads to have vertebrobasilar atherosclerotic plaques. Vertebrobasilar artery plaques were examined with 3.0 T HR-MRI to evaluate the plaque nature and stability. According to the results of plaque stability, the plaques were divided into stable group (16 cases) and unstable group (14 cases). Follow up for 24 months, record and compare the time and proportion of the first visit to the occurrence of circulatory infarction between the two groups. Results the time of posterior circulation infarction in unstable group was significantly shorter than that in stable group, and the difference was statistically significant [11.5 (7.0 卤20.0) months vs 24.0 (22.5 卤24.0) months (P 0.05)]. The proportion of posterior circulatory infarction in stable group and unstable group was 5 / 168 / 14, respectively. There was no significant difference between the two groups (P0.05). Conclusion HR-MRI evaluation of vertebral-basilar atherosclerotic plaque is valuable for the progression of posterior circulation ischemic disease.
【作者单位】：常熟市第一人民医院神经内科;常熟市第一人民医院医学影像科;
【基金】：常熟市科技发展计划(社会发展)项目(CS201421)
【分类号】：R743.3

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