脑桥梗死危险因素、临床特征和CISS分型及与前循环梗死比较
发布时间：2018-08-13 17:46
【摘要】：目的：探讨单纯性脑桥梗死的危险因素、临床特征和CISS分型。方法：回顾性分析2009年1月至2012年12月期间,在我院神经内科连续住院的急性脑梗死患者,单纯性脑桥梗死作为病例组,前循环脑梗死为对照组,探讨脑桥梗死的危险因素、临床表现及CISS分型。结果：单因素分析结果显示,与前循环梗死比较,单纯性脑桥梗死组危险因素中糖尿病者(53.6%vs34.1%,P=0.030)、糖化血红蛋白(7.2±1.6vs6.6±1.7,P=0.006)、低密度脂蛋白(2.4±0.7vs2.7±0.9,P=0.003)等的差异有统计学意义(p0.05)；多因素logistic回归分析结果示,糖化血红蛋白(OR1.183,95%CI1.007-1.389,P=0.041)可能是单纯性脑桥梗死的独立危险因素,持续吸烟(OR0.484,95%CI0.264-0.885,P=0.018)、低密度脂蛋白(OR0.593,95%CI0.435-0.808,P=0.001)说明脑桥梗死患者持续吸烟、低密度脂蛋白比例低于前循环梗死者；单纯性脑桥梗死及前循环梗死组临床特征分析的结果显示,头晕／眩晕(46.3%vs21.6%,P=0.000)、恶心呕吐(26.3%vs7.8%,P=0.000)、行走不稳(29.5%vs10.2%P=0.000)、复视(10.5%vs1.2%,P=0.000)、耳鸣(6.3%vs0.3%,P=0.000)、听力下降(6.3%vs0.6%,P=0.001)、视物模糊(7.4%vs2.1%,P=0.026)等症状比较的差异有统计学意义(p0.05)；共济失调(38.9%vs28.1%,P=0.044)、单肢感觉障碍(7.4%vs2.4%,P=0.044)、眼外肌麻痹(8.4%vs1.5%,P=0.002)、眼球震颤(14.7%vs1.5%,P=0.000)、失语(1.1%vs15.6%,p=0.000)、交叉性感觉障碍(2.1%vs0,P=0.049)、周围性面瘫(2.1%vs0,P=0.049)、交叉性运动障碍(8.4%vs0,P=0.000)等体征比较的差异有统计学意义(p0.05)；纳入多因素logistic回归分析结果示,头晕/眩晕(OR1.827,95%CI1.024-3.259,P=0.041)、恶心呕吐(OR2.631,95%CI1.267-5.464,P=0.009)、复视(OR5.103,95%CI1.342-19.404,P=0.017)、耳鸣(OR10.512,95%CI1.119-98.714,P=0.040)、行走不稳(OR2.547,95%CI1.328-4.884,P=0.005)、眼球震颤(OR9.368,95%CI3.251-26.991,P=0.000)和单肢感觉障碍(OR3.145,95%CI1.051-9.412)等可能与单纯脑桥梗死有关；上述2组CISS分型分析结果显示,大动脉粥样硬化型(25.2%vs41.3%P=0.005)、穿支动脉疾病(65.3%vs44.0%,P=0.000)等的比较均有显著性差异,纳入多因素logistic回归分析,结果示穿支动脉疾病(OR2.343,95%CI1.086-5.057,P=0.030)可能与单纯脑桥梗死有关。结论：单纯脑桥梗死的危险因素、临床特征和CISS分型与前循环梗死不同,危险因素中糖化血红蛋白与脑桥梗死相关,持续吸烟、低密度脂蛋白与前循环梗死相关；头晕、恶心呕吐、复视、行走不稳、眼球震颤、耳鸣和单肢感觉障碍为单纯性脑桥梗死的临床特征；脑桥梗死的病因分型中穿支动脉疾病更多。
[Abstract]:Objective: to investigate the risk factors, clinical features and CISS classification of simple pons infarction. Methods: from January 2009 to December 2012, the patients with acute cerebral infarction (ACI) in neurology department of our hospital were analyzed retrospectively. Simple pons infarction was used as the case group and anterior circulation infarction as control group. The risk factors of pons infarction were discussed. Clinical manifestation and CISS classification. Results: the results of univariate analysis showed that there were significant differences in the risk factors of diabetes mellitus (53.6 vs 34.1g / P 0.030), glycosylated hemoglobin (7.2 卤1.6vs6.6 卤1.7) and low density lipoprotein (2.4 卤0.7vs2.7 卤0.9 P 0.003) between patients with simple pontine infarction and those with anterior circulation infarction. The results of multivariate logistic regression analysis showed that glycosylated hemoglobin (OR1.183C95CI1.007-1.389P0.041) may be an independent risk factor for simple pontine infarction. Continuous smoking (OR0.484C95CI0.264-0.885P0. 018) and low density lipoprotein (OR0.59395CI0.435-0.808Pn0. 001) indicated that patients with pontine infarction continued to smoke. The ratio of low density lipoprotein (LDL) was lower than that of patients with anterior circulation infarction (ACI), and the clinical characteristics of patients with simple pons infarction and anterior circulation infarction (ACI) were analyzed. Dizziness / dizziness (46.3vs21.6P0.000), nausea and vomiting (26.3vs7.8), 29.5%vs10.2%P=0.000, diplopia (10.5vs1.2), tinnitus (6.3vs0.3P0.000), hearing loss (6.3vs0.65P0.000), blurred vision (7.4vs2.1m P0.026) were statistically significant (p0.05). 鍏辨祹澶辫皟(38.9%vs28.1%,P=0.044),鍗曡偄鎰熻闅滅(7.4%vs2.4%,P=0.044),鐪煎鑲岄夯鐥，
本文编号：2181727
[Abstract]:Objective: to investigate the risk factors, clinical features and CISS classification of simple pons infarction. Methods: from January 2009 to December 2012, the patients with acute cerebral infarction (ACI) in neurology department of our hospital were analyzed retrospectively. Simple pons infarction was used as the case group and anterior circulation infarction as control group. The risk factors of pons infarction were discussed. Clinical manifestation and CISS classification. Results: the results of univariate analysis showed that there were significant differences in the risk factors of diabetes mellitus (53.6 vs 34.1g / P 0.030), glycosylated hemoglobin (7.2 卤1.6vs6.6 卤1.7) and low density lipoprotein (2.4 卤0.7vs2.7 卤0.9 P 0.003) between patients with simple pontine infarction and those with anterior circulation infarction. The results of multivariate logistic regression analysis showed that glycosylated hemoglobin (OR1.183C95CI1.007-1.389P0.041) may be an independent risk factor for simple pontine infarction. Continuous smoking (OR0.484C95CI0.264-0.885P0. 018) and low density lipoprotein (OR0.59395CI0.435-0.808Pn0. 001) indicated that patients with pontine infarction continued to smoke. The ratio of low density lipoprotein (LDL) was lower than that of patients with anterior circulation infarction (ACI), and the clinical characteristics of patients with simple pons infarction and anterior circulation infarction (ACI) were analyzed. Dizziness / dizziness (46.3vs21.6P0.000), nausea and vomiting (26.3vs7.8), 29.5%vs10.2%P=0.000, diplopia (10.5vs1.2), tinnitus (6.3vs0.3P0.000), hearing loss (6.3vs0.65P0.000), blurred vision (7.4vs2.1m P0.026) were statistically significant (p0.05). 鍏辨祹澶辫皟(38.9%vs28.1%,P=0.044),鍗曡偄鎰熻闅滅(7.4%vs2.4%,P=0.044),鐪煎鑲岄夯鐥，
本文编号：2181727
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