中枢神经系统表面含铁血黄素沉积症的磁共振成像研究
发布时间：2018-08-30 12:00
【摘要】：目的： 探讨中枢神经系统表面含铁血黄素沉积症(superficial siderosis,SS)的影像表现。方法： 应用西门子3.0T磁共振成像系统(Verio,Siemens Medical Systems,Erlangen, Germany),对具有2年以上颅脑创伤或手术病史的患者行MRI检查,参数如下：轴位T1WI(TI/TR/TE:823/1900/9),T2WI(TR/TE:6000/96),T2-FLAIR (TI/TR/TE:2140/6600/94),T2*WI(TR/TE:620/20),矢状位T1WI,T2WI及MR脑池造影(TR/TE:1500/224)。 结果： 中枢神经系统表面含铁血黄素沉积症是一种少见的神经系统疾病,主要表现为双侧感音性耳聋、共济失调及脊髓病变。常见致病原因是慢性蛛网膜下腔出血所致的含铁血黄素沉积于脑和脊髓表面,需要依据磁共振T2WI图像上所显示的T2低信号来进行诊断,当MRI变化轻微时,可能会延缓该病的诊断,因此准确的临床评价及正确的影像检查技术可最大限度地使该病得以诊断。MRI图像显示含铁血黄素沉积于脑及脊髓软膜,T2WI序列显示为特征性的线样低信号。为避免中枢神经系统的不可逆损害,即便是该病相关的微小MR征象也不应被低估。SS的影像学表现与蛛网膜下腔出血相关。SS是慢性蛛网膜下腔出血沉积于脑和脊髓表面。经典三联征包括双侧感音性耳聋、共济失调及脊髓病变,而且T2MRI的特异性征象为脑干、小脑及脊髓表面的低信号。可导致慢性蛛网膜下腔出血的常见原因包括中枢神经系统肿瘤,头颈部创伤,动静脉畸形等,仍有近三分之一病例的病因不明。如该病被早期发现,可以通过遏制出血来源进行治疗,但该病的自然病程是一种渐进性的神经系统功能的低下。 结论： 中枢神经系统的SS为少见的综合征,行MRI检查,尤其T2WI序列具有重要诊断价值。
[Abstract]:Objective: to investigate the imaging features of hemosiderosis (superficial siderosis,SS) on the surface of the central nervous system (CNS). Methods: Siemens 3.0T magnetic resonance imaging system (Verio,Siemens Medical Systems,Erlangen, Germany),) was used to examine MRI in patients with more than 2 years history of craniocerebral trauma or surgery. The parameters were as follows: axial T1WI (TI/TR/TE:823/1900/9) T2WI (TR/TE:6000/96) T2-flair (TI/TR/TE:2140/6600/94) T2-flair T2WI (TR/TE:620/20), sagittal T1WII-T2WI and MR cisternography (TR/TE:1500/224). Results: hemosiderin deposition on the surface of central nervous system is a rare disease of nervous system with bilateral sensorineural deafness ataxia and myelopathy. The common cause is the deposition of hemosiderin on the surface of the brain and spinal cord due to chronic subarachnoid hemorrhage, which needs to be diagnosed on the basis of T 2 low signal intensity shown on T2WI images. When MRI changes slightly, May delay the diagnosis of the disease, Therefore, accurate clinical evaluation and correct imaging techniques can maximize the diagnosis of the disease. MRI images show that hemosiderin is deposited in the brain and spinal cord pial membrane on T2WI sequence showing characteristic linear hypotension. In order to avoid irreversible damage to the central nervous system, even small MR signs associated with the disease should not be underestimated. The imaging findings of SS are associated with subarachnoid hemorrhage. SS is a chronic subarachnoid hemorrhage deposited on the surface of the brain and spinal cord. Classic triple signs include bilateral sensorineural deafness, ataxia and spinal cord lesions, and the specific signs of T2MRI are low signal intensity on the surface of the brain stem, cerebellum and spinal cord. The common causes of chronic subarachnoid hemorrhage include central nervous system tumor, head and neck trauma, arteriovenous malformation and so on. If the disease is detected early, it can be treated by curbing the source of bleeding, but the natural course of the disease is a progressive decline in nervous system function. Conclusion: SS in central nervous system is a rare syndrome. MRI examination, especially T2WI sequence, has important diagnostic value.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.2;R741
本文编号：2213012
[Abstract]:Objective: to investigate the imaging features of hemosiderosis (superficial siderosis,SS) on the surface of the central nervous system (CNS). Methods: Siemens 3.0T magnetic resonance imaging system (Verio,Siemens Medical Systems,Erlangen, Germany),) was used to examine MRI in patients with more than 2 years history of craniocerebral trauma or surgery. The parameters were as follows: axial T1WI (TI/TR/TE:823/1900/9) T2WI (TR/TE:6000/96) T2-flair (TI/TR/TE:2140/6600/94) T2-flair T2WI (TR/TE:620/20), sagittal T1WII-T2WI and MR cisternography (TR/TE:1500/224). Results: hemosiderin deposition on the surface of central nervous system is a rare disease of nervous system with bilateral sensorineural deafness ataxia and myelopathy. The common cause is the deposition of hemosiderin on the surface of the brain and spinal cord due to chronic subarachnoid hemorrhage, which needs to be diagnosed on the basis of T 2 low signal intensity shown on T2WI images. When MRI changes slightly, May delay the diagnosis of the disease, Therefore, accurate clinical evaluation and correct imaging techniques can maximize the diagnosis of the disease. MRI images show that hemosiderin is deposited in the brain and spinal cord pial membrane on T2WI sequence showing characteristic linear hypotension. In order to avoid irreversible damage to the central nervous system, even small MR signs associated with the disease should not be underestimated. The imaging findings of SS are associated with subarachnoid hemorrhage. SS is a chronic subarachnoid hemorrhage deposited on the surface of the brain and spinal cord. Classic triple signs include bilateral sensorineural deafness, ataxia and spinal cord lesions, and the specific signs of T2MRI are low signal intensity on the surface of the brain stem, cerebellum and spinal cord. The common causes of chronic subarachnoid hemorrhage include central nervous system tumor, head and neck trauma, arteriovenous malformation and so on. If the disease is detected early, it can be treated by curbing the source of bleeding, but the natural course of the disease is a progressive decline in nervous system function. Conclusion: SS in central nervous system is a rare syndrome. MRI examination, especially T2WI sequence, has important diagnostic value.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.2;R741
【共引文献】
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相关硕士学位论文 前2条
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