肥大细胞和脑神经炎症相关疾病
发布时间：2018-09-08 15:23
【摘要】：正1890年,Neumann~([1])首次在多发性脑硬化患者的脑硬化斑块边缘发现肥大细胞(Mast cells,MCs)~([2])。大量实验表明脑部MCs分泌或活化释放的物质参与脑内炎症反应以及神经系统炎症的病理过程,如自闭症谱系障碍、多发性脑硬化和阿尔兹海默症~([3,4])。自闭症谱系障碍(Autism spectrum disorder,ASD)是一种和神经炎症有关的神经发展性障碍,患者的交流和行为存在缺陷。根据2012年美国
[Abstract]:In 1890, Neumann ~ (1) was the first to find mast cells (Mast cells,MCs) on the edge of multiple brain sclerosis (MS) plaques. A large number of experiments have shown that the MCs secreted or activated by the brain is involved in the pathological processes of inflammation in the brain and inflammation of the nervous system, such as autism spectrum disorders, multiple brain sclerosis and Alzheimer's disease. Autism spectrum disorder (Autism spectrum disorder,ASD) is a neurodevelopmental disorder associated with neuroinflammation. According to the United States in 2012,
【作者单位】： 常州大学制药与生命科学学院;
【基金】：常州大学人才引进基金(ZMF14020066) 常州科技局国际交流研究基金(KYJ1520305)资助
【分类号】：R741
，
本文编号：2230913
[Abstract]:In 1890, Neumann ~ (1) was the first to find mast cells (Mast cells,MCs) on the edge of multiple brain sclerosis (MS) plaques. A large number of experiments have shown that the MCs secreted or activated by the brain is involved in the pathological processes of inflammation in the brain and inflammation of the nervous system, such as autism spectrum disorders, multiple brain sclerosis and Alzheimer's disease. Autism spectrum disorder (Autism spectrum disorder,ASD) is a neurodevelopmental disorder associated with neuroinflammation. According to the United States in 2012,
【作者单位】： 常州大学制药与生命科学学院;
【基金】：常州大学人才引进基金(ZMF14020066) 常州科技局国际交流研究基金(KYJ1520305)资助
【分类号】：R741
，
本文编号：2230913
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