D-二聚体与脑梗死发病时间及溶栓前后NIHSS评分的关系

发布时间：2018-10-13 20:21

【摘要】：目的:探讨急性脑梗死患者溶栓前D-二聚体浓度与脑梗死发病至就诊时间、脑梗死症状严重程度、症状改善情况之间的关系。方法:研究纳入了117例患者,依据入院时D-二聚体浓度,将患者分为D-二聚体0.55 mg/L组(正常组)与D-二聚体≥0.55 mg/L组(异常组),比较两组在发病至就诊时间、溶栓前美国国立卫生研究院卒中量表(National Institutes of Health Stroke Scale,NIHSS)评分、溶栓后NIHSS评分改善程度之间的差异。结果:两组在发病至就诊时间上差异无统计学意义[(122.4±57.5)min vs.(116.6±59.4)min,P0.05],正常组溶栓前NIHSS评分明显低于异常组[(9.6±6.8)分vs.(17.4±9.2)分,P0.05],两组在溶栓后NIHSS评分改善程度之间差异无统计学意义[(3.6±5.4)分vs.(5.0±7.6)分,P0.05]。结论:不同D-二聚体浓度与发病至就诊时间无明显关系,D-二聚体异常组入院时NIHSS评分显著高于正常组,两组在溶栓后NIHSS评分的改善程度上差异无统计学意义。
[Abstract]:Objective: to investigate the relationship between the concentration of D-dimer before thrombolytic therapy and the onset time of cerebral infarction, the severity of cerebral infarction symptoms and the improvement of symptoms in patients with acute cerebral infarction. Methods: according to the concentration of D-dimer at admission, the patients were divided into two groups: Ddimer 0.55 mg/L group (normal group) and D-dimer 鈮，

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