皮肤交感反射和肛门括约肌肌电图在帕金森病患者诊断中的价值

发布时间：2018-11-05 10:58

【摘要】：目的探讨皮肤交感反射(SSR)和肛门括约肌肌电图(EAS-EMG)对帕金森病(PD)患者的诊断价值。方法 45例PD患者作观察组,另外选择同期健康体检者45例为对照组。两组均采用PD自主神经症状量表(SCOPA-AUT)对神经功能进行评估,并实施SSR和EAS-EMG检测,分析SSR与EAS-EMG对PD患者的诊断价值。结果观察组SCOPA-AUT得分≥1分31例,1分14例,对照组SCOPA-AUT得分≥1分0例,1分45例,观察组SCOPA-AUT得分显著高于对照组(P0.05)。SSR显示观察组的上下肢潜伏期均明显大于对照组,上下肢的波幅明显少于对照组(P0.05)。EAS-EMG检测显示观察组存在自主神经功能障碍患者平均时限及多相波百分比明显高于无自主神经功能障碍患者(P0.05),两组平均波幅比较无统计学差异(P0.05)。经Pearson相关性分析显示,观察组的自主神经功能障碍患者中SCOPA-AUT得分与上下肢的SSR波幅不相关(r=0.216,0.134;P=0.245,0.317),与上下肢的SSR潜伏期呈正相关(r=0.487,0.551;P=0.023,0.016)。SCOPA-AUT得分与EAS-EMG的运动单位电位(MUAP)平均波幅不相关(r=0.234,P=0.224),与MUAP的多相波百分比、平均时限呈正相关(r=0.514,0.547;P=0.013,0.011)。结论SSR及EAS-EMG可用于评估PD患者的自主神经功能,能够为PD患者的诊断提供依据。
[Abstract]:Objective to evaluate the diagnostic value of skin sympathetic reflex (SSR) and anal sphincter electromyography (EAS-EMG) in patients with Parkinson's disease (PD). Methods 45 patients with PD were selected as observation group and 45 healthy persons as control group. PD autonomic nervous symptom scale (SCOPA-AUT) was used to evaluate the neurological function and SSR and EAS-EMG were performed to analyze the diagnostic value of SSR and EAS-EMG in PD patients. Results there were 31 cases with SCOPA-AUT score 鈮，

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