免疫对神经行为学的影响及机制的最新进展
发布时间：2018-11-25 17:26
【摘要】：在生理或病理状态下,免疫系统与中枢神经系统之间都存在着密切的交流。多种免疫细胞及其相关细胞因子可通过某些途径进入大脑,对神经细胞产生多种神经生物学作用,进而引起认知、情感、社会行为等多个方面的神经行为学改变。本文回顾了几种重要的免疫细胞及细胞因子对神经行为学的影响,阐明其神经免疫学机制,为预防急慢性炎症性疾病导致的神经行为学异常提供预警。
[Abstract]:There is close communication between the immune system and the central nervous system in physiological or pathological state. Many kinds of immune cells and their related cytokines can enter the brain through some ways, which can produce many neurobiological effects on nerve cells, and then cause neurobehavioral changes in many aspects, such as cognition, emotion, social behavior and so on. In this paper, the effects of several important immune cells and cytokines on neurobehavioral science are reviewed, and the neuroimmunological mechanism is clarified, which provides a warning for the prevention of neurobehavioral abnormalities caused by acute and chronic inflammatory diseases.
【作者单位】： 解放军总医院第一附属医院创伤外科研究室;武警8640部队医院;温州医科大学附属第一医院急诊中心;
【基金】：国家自然科学基金(81272089) 国家重点基础研究发展计划项目(2012CB518102) 全军“十二五”计划重点项目(BWSl2J050)
【分类号】：R741
本文编号：2356885
[Abstract]:There is close communication between the immune system and the central nervous system in physiological or pathological state. Many kinds of immune cells and their related cytokines can enter the brain through some ways, which can produce many neurobiological effects on nerve cells, and then cause neurobehavioral changes in many aspects, such as cognition, emotion, social behavior and so on. In this paper, the effects of several important immune cells and cytokines on neurobehavioral science are reviewed, and the neuroimmunological mechanism is clarified, which provides a warning for the prevention of neurobehavioral abnormalities caused by acute and chronic inflammatory diseases.
【作者单位】： 解放军总医院第一附属医院创伤外科研究室;武警8640部队医院;温州医科大学附属第一医院急诊中心;
【基金】：国家自然科学基金(81272089) 国家重点基础研究发展计划项目(2012CB518102) 全军“十二五”计划重点项目(BWSl2J050)
【分类号】：R741
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