帕瑞昔布钠对急性脑梗死患者疗效、炎症指标及肾功能的影响
发布时间：2018-12-17 17:34
【摘要】：目的探讨帕瑞昔布钠对急性脑梗死(ACI)患者疗效、炎症指标及肾功能的影响。方法选择ACI患者89例,随机分为观察组46例和对照组43例。两组均给予常规治疗及尿激酶溶栓治疗,观察组加用帕瑞昔布钠治疗。治疗前及治疗1周后,比较两组患者的炎症和肾功能指标水平、美国国立卫生研究院卒中量表(NIHSS)评分、急性生理与慢性健康评估(APACHEⅡ)评分。结果治疗后两组的超敏C反应蛋白、肿瘤坏死因子-α(TNF-α)、白细胞介素-6、胱抑素、血尿素氮、血清肌酐水平以及APACHEⅡ、NIHSS评分均较前降低(除外TNF-α,均P0.05),且观察组以上指标均低于对照组(均P0.05)。结论帕瑞昔布钠能够改善ACI患者的神经功能缺损情况及保护肾功能,其可能通过抑制炎症介质的大量释放、控制炎症反应而实现。
[Abstract]:Objective to investigate the effect of paroxib sodium on (ACI) patients with acute cerebral infarction. Methods 89 patients with ACI were randomly divided into observation group (n = 46) and control group (n = 43). Both groups were treated with routine therapy and urokinase thrombolytic therapy. The inflammatory and renal function indexes, (NIHSS) score and APACHE 鈪，
本文编号：2384564
[Abstract]:Objective to investigate the effect of paroxib sodium on (ACI) patients with acute cerebral infarction. Methods 89 patients with ACI were randomly divided into observation group (n = 46) and control group (n = 43). Both groups were treated with routine therapy and urokinase thrombolytic therapy. The inflammatory and renal function indexes, (NIHSS) score and APACHE 鈪，
本文编号：2384564
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