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H_p感染对帕金森病患者运动水平的影响研究

发布时间:2019-01-02 07:47
【摘要】:目的探讨Hp感染对帕金森病患者运动水平的影响,为临床治疗提供参考依据。方法选取2014年5月-2016年5月医院住院治疗的帕金森病患者96例,根据是否发生感染将患者分为Hp感染组51例和非Hp感染组45例,治疗13周后,比较两组患者的总体疗效、运动水平。结果 Hp感染组患者显效比例和总有效率显著的高于非Hp感染组,差异有统计学意义(P0.05);治疗后,与治疗前相比,Hp感染组患者UPDRS-Ⅳ量表评分显著降低,Hp感染组患者的UPDRS-Ⅳ量表评分显著低于非Hp感染组,差异均有统计学意义(P0.05);治疗前,两组患者"开、关"期时间的差异无统计学意义,治疗后,Hp感染组患者"开"期时间显著长于非Hp感染组,Hp感染组患者"关"期时间显著短于非Hp感染组,差异均有统计学意义(P0.05)。结论清除Hp后可以有效的提升帕金森病患者的运动水平,降低运动并发症,延缓"开关"现象,并提升患者的总体疗效,但是具体的作用机制尚不明确,还需进一步深入研究,为改善帕金森病患者的疗效提供新的治疗途径。
[Abstract]:Objective to investigate the effect of Hp infection on the exercise level of Parkinson's disease (PD) patients and to provide reference for clinical treatment. Methods 96 patients with Parkinson's disease who were hospitalized from May 2014 to May 2016 were divided into Hp infection group (n = 51) and non-Hp infection group (n = 45). After 13 weeks of treatment, the overall efficacy of the two groups was compared. Level of movement Results the effective rate and total effective rate of Hp infection group were significantly higher than that of non-Hp infection group (P0.05). After treatment, the scores of UPDRS- 鈪,

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