女性帕金森病患者经期影响的相关因素分析
发布时间：2019-01-09 18:46
【摘要】：目的调查育龄期女性帕金森病(PD)患者受经期影响的患病率及临床特征。方法采用调查问卷、病例对照研究,连续选取自2015年6月~2016年1月我院门诊及天坛医院PD专病门诊发病年龄在50岁以下女性PD患者,记录受经期影响的病例数,分为经期相关组和与经期无关组,分析两组临床的异质性。同时收集两组发病年龄、文化程度、初始症状、病程、有无毒物接触史、家族史、统一PD评定量表第Ⅲ部分(UPDRS-Ⅲ)评分、改良Hoehn-Yahr(H-Y)分级、贝克焦虑量表(BAI)等资料。结果共收集175例女性PD患者,经期受影响者42例,患病率为24%;将经期相关组与经期无关组分别在非经期及经期期间进行比较,非经期期间,两组在发病年龄、BAI方面差异有统计学意义(均P0.05),而在病程、文化程度、有无毒物接触史、家族史、UPDRS-Ⅲ、改良H-Y分级等方面则差异无统计学意义(均P0.05),但在经期期间,两组在发病年龄、UPDRS-Ⅲ、改良H-Y分级、BAI等方面均存在明显统计学意义(均P0.000)。结论女性育龄期PD患者易受经期影响,临床症状恶化,表现为运动症状加重,更易合并焦虑,提示该类患者日常生活能力及生活质量更差,应提醒临床医生的识别。
[Abstract]:Objective to investigate the prevalence and clinical characteristics of (PD) patients with Parkinson's disease at childbearing age. Methods from June 2015 to January 2016, female patients with PD under 50 years of age were selected from our outpatient clinic and Temple of Heaven Hospital from June 2015 to January 2016. The number of cases affected by menstrual period was recorded. The clinical heterogeneity of the two groups was analyzed. At the same time, age of onset, education level, initial symptoms, course of disease, history of exposure to poisons, family history, unified PD rating scale part 鈪，
本文编号：2405960
[Abstract]:Objective to investigate the prevalence and clinical characteristics of (PD) patients with Parkinson's disease at childbearing age. Methods from June 2015 to January 2016, female patients with PD under 50 years of age were selected from our outpatient clinic and Temple of Heaven Hospital from June 2015 to January 2016. The number of cases affected by menstrual period was recorded. The clinical heterogeneity of the two groups was analyzed. At the same time, age of onset, education level, initial symptoms, course of disease, history of exposure to poisons, family history, unified PD rating scale part 鈪，
本文编号：2405960
本文链接：https://www.wllwen.com/yixuelunwen/shenjingyixue/2405960.html
最近更新
教材专著
