事件相关电位、动态脑电图联合脑干听觉诱发电位对昏迷患者预后的评估价值

发布时间：2019-01-28 08:18

【摘要】：目的探讨事件相关电位(ERP)、动态脑电图(AEEG)联合脑干听觉诱发电位(BAEP)对昏迷患者预后的评估价值。方法选取100例昏迷患者作为研究对象。对昏迷患者进行ERP、AEEG及BAEP检测,采用Spearman相关性分析昏迷患者AEEG分级和BAEP分级与GOS评分的相关性,并探讨ERP、AEEG联合BAEP对昏迷预后的评估价值。结果 Spearman相关性分析发现,昏迷患者入院1 w内AEEG分级与昏迷发生3个月后GOS评分呈负相关(r=-0.715 2,P=0.000);昏迷患者入院1 w内BAEP分级与昏迷发生3个月后GOS评分呈负相关(r=-0.632 6,P=0.000)。患者入院1 w内行ERP、AEEG联合BAEP检测对昏迷患者预后进行评估,其敏感性(SE)、特异性(SP)、对预后评估的准确率(AC)优于格拉斯哥昏迷评分(GCS)、ERP、AEEG以及BAEP(P0.05),而预后评估的错误率(FA)均低于GCS、ERP、AEEG以及BAEP。结论 ERP、AEEG联合BAEP可以作为评估昏迷患者预后的重要手段,值得推广。
[Abstract]:Objective to evaluate the prognostic value of event-related potential (ERP),) dynamic electroencephalogram (AEEG) combined with brainstem auditory evoked potential (BAEP) in coma patients. Methods 100 coma patients were selected as study objects. ERP,AEEG and BAEP were detected in coma patients. Spearman correlation analysis was used to analyze the correlation between AEEG grade, BAEP grade and GOS score in coma patients, and to explore the value of ERP,AEEG combined with BAEP in evaluating the prognosis of coma. Results Spearman correlation analysis showed that there was a negative correlation between AEEG grade and GOS score 3 months after coma (r = -0.7152, P = 0.000). There was a negative correlation between the BAEP grade and the GOS score 3 months after the coma (r = -0.632 6, P = 0.000). The prognosis of coma patients was evaluated by ERP,AEEG and BAEP within 1 week of admission. The sensitivity of (SE), specific (SP), was better than that of Glasgow coma score (GCS), ERP,) in evaluating prognosis. AEEG and BAEP (P0.05), and (FA) of prognosis evaluation were lower than GCS,ERP,AEEG and BAEP.. Conclusion ERP,AEEG combined with BAEP can be used to evaluate the prognosis of coma patients.
【作者单位】：贵州医科大学第二附属医院神经内科;
【分类号】：R741.04

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