诊断时间延迟对颅内静脉窦血栓形成患者临床特征及预后相关性的影响
发布时间:2019-02-11 20:13
【摘要】:目的颅内静脉窦血栓形成(CVST)误诊率较高,而关于CVST诊断时间与患者临床特征及预后之间的相关性研究较少,文中旨在探讨CVST患者的临床特征与其诊断时间长短之间的关系,并分析延迟诊断对患者预后的影响。方法回顾性分析2004年3月至2016年8月南京军区南京总医院神经内科收治的94例CVST住院患者临床资料。根据四分位诊断时间将患者分为5 d组、5~9 d组、10~16 d组、16 d组,主要研究终点是患者出院后3个月的改良RANKIN量表(modified Rankin Scale scorem,mRS)评分≤1分,次要研究终点是患者出院后3个月的mRS评分≤2分。并分析CVST患者延迟诊断时间与临床特征之间的相互关系。结果 CVST延迟诊断时间与视乳头水肿、孤立性颅内高压综合征、癫痫、颅内病灶、GCS评分有关(P0.05);视乳头水肿、孤立性颅内高压综合征、GCS评分14~15分需要更长的诊断时间;癫痫、存在脑出血或梗塞病灶所需诊断时间较短。实验室指标中,低清蛋白水平、低总蛋白水平、高凝血酶时间、及高C反应蛋白水平的患者所需诊断时间较短(P0.05)。延迟诊断时间的长短与CVST患者的mRS评分没有相关性(P0.05)。结论为避免延迟诊断可以以CVST患者入院时的症状及实验室指标为体征及标志物,为指导临床CVST的早期诊断提供新的参考。
[Abstract]:Objective the misdiagnosis rate of intracranial venous sinus thrombosis (CVST) is high, but the correlation between the diagnosis time of CVST and the clinical characteristics and prognosis of the patients is less studied. The purpose of this paper is to explore the relationship between the clinical characteristics and the duration of diagnosis of CVST patients. The effect of delayed diagnosis on prognosis was analyzed. Methods from March 2004 to August 2016, the clinical data of 94 inpatients with CVST in Department of Neurology, Nanjing General Hospital of Nanjing military region were retrospectively analyzed. According to the diagnostic time of quartile, the patients were divided into 5 d group, 5 d group, 10 d group, 16 d group. The main end point of the study was the modified RANKIN scale (modified Rankin Scale scorem,mRS) score 鈮,
本文编号:2420064
[Abstract]:Objective the misdiagnosis rate of intracranial venous sinus thrombosis (CVST) is high, but the correlation between the diagnosis time of CVST and the clinical characteristics and prognosis of the patients is less studied. The purpose of this paper is to explore the relationship between the clinical characteristics and the duration of diagnosis of CVST patients. The effect of delayed diagnosis on prognosis was analyzed. Methods from March 2004 to August 2016, the clinical data of 94 inpatients with CVST in Department of Neurology, Nanjing General Hospital of Nanjing military region were retrospectively analyzed. According to the diagnostic time of quartile, the patients were divided into 5 d group, 5 d group, 10 d group, 16 d group. The main end point of the study was the modified RANKIN scale (modified Rankin Scale scorem,mRS) score 鈮,
本文编号:2420064
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