动态脉压与颅内动脉狭窄程度的相关性

发布时间：2019-03-15 08:31

【摘要】：目的探讨24 h动态脉压与颅内动脉狭窄程度之间的关系。方法选取165例颅内动脉狭窄的缺血性脑卒中患者作为狭窄组,142例无明显颅内动脉狭窄患者作为对照组,并依据北美症状性颈动脉狭窄试验法,将狭窄组患者进行颅内动脉狭窄程度分级。所有患者采用无创性携带式动态血压监测仪进行观察,记录患者24 h平均收缩压、舒张压以及动态脉压。结果颅内动脉狭窄组动态脉压[(73.02±10.86)mmHg]显著高于无颅内动脉狭窄的对照组[(59.63±12.96)mmHg,P0.01];中度狭窄组动态脉压[(69.73±9.3)mmHg]显著高于无狭窄的对照组[(59.63±12.96)mmHg,P0.01];重度狭窄组动态脉压[(77.36±7.94)mmHg]显著高于中度狭窄组[(69.73±9.3)mmHg,P0.05];动态脉压与颅内动脉狭窄的发生独立相关(OR值为1.092)。结论动态脉压与颅内动脉狭窄及其狭窄程度具有显著相关性,且动态脉压是颅内动脉狭窄的独立危险因素。
[Abstract]:Objective to investigate the relationship between 24-hour dynamic pulse pressure and the degree of intracranial artery stenosis. Methods 165 ischemic stroke patients with intracranial artery stenosis were selected as the stenosis group, 142 patients without obvious intracranial artery stenosis were selected as the control group, and the symptomatic carotid artery stenosis test was conducted in North America. The degree of intracranial artery stenosis was graded in the stenosis group. All patients were observed with a non-invasive portable ambulatory blood pressure monitor. The mean systolic blood pressure, diastolic blood pressure and dynamic pulse pressure of the patients were recorded. Results the dynamic pulse pressure in patients with intracranial artery stenosis [(73.02 卤10.86) mmHg] was significantly higher than that in the control group without intracranial artery stenosis [(59.63 卤12.96) mmHg,P0.01]. The dynamic pulse pressure in the moderate stenosis group [(69.73 卤9.3) mmHg] was significantly higher than that in the control group without stenosis [(59.63 卤12.96) mmHg,P0.01]. The dynamic pulse pressure in severe stenosis group [(77.36 卤7.94) mmHg] was significantly higher than that in moderate stenosis group [(69.73 卤9.3) mmHg,P0.05], and the dynamic pulse pressure was independently correlated with the occurrence of intracranial artery stenosis (OR = 1.092). Conclusion there is a significant correlation between dynamic pulse pressure and intracranial artery stenosis and its degree, and dynamic pulse pressure is an independent risk factor for intracranial artery stenosis.
【作者单位】：解放军98医院神经外科;
【分类号】：R743.3

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