甘露醇、胞二磷胆碱联合中药治疗肺性脑病的疗效研究

发布时间：2019-03-17 10:09

【摘要】：目的探讨甘露醇、胞二磷胆碱联合中药治疗肺性脑病的疗效。方法选取2015年2月~2016年1月我院收治的肺性脑病患者128例作为研究对象,随机分为对照组与治疗组,各64例。对照组予以控制呼吸道感染、保持呼吸道通畅、纠正缺氧和二氧化碳潴留、纠正酸碱电解质失衡、酌情补钾或呼吸兴奋剂等基础疗法,治疗组在此基础上,予以甘露醇、胞二磷胆碱联合中医中药治疗。结果两组患者治疗后疗效比较,经治疗后治疗组总有效率为75%,对照组总有效率为39.1%。两组比较,差异有统计学意义(P0.05);两组患者治疗前后血气指标比较,两组患者治疗前缺氧和CO2潴留明显,治疗后两组患者血气分析各项指标均有改善,与治疗前相比,差异有统计学意义(P0.05)。结论甘露醇、胞二磷胆碱联合中药治疗肺性脑病具有方便、简单、疗效好、无毒副作用,患者易接受等优点,值得在临床推广应用。
[Abstract]:Objective to investigate the therapeutic effect of mannitol and citicoline combined with traditional Chinese medicine on pulmonary encephalopathy. Methods from February 2015 to January 2016, 128 patients with pulmonary encephalopathy were randomly divided into control group (n = 64) and treatment group (n = 64). In the control group, respiratory tract infection was controlled, respiratory tract patency was maintained, hypoxia and carbon dioxide retention were corrected, acid-base electrolyte imbalance was corrected, potassium or respiratory stimulant and other basic therapies were given as appropriate. On this basis, mannitol was given to the treatment group. Treatment of citicoline combined with traditional Chinese medicine. Results after treatment, the total effective rate was 75% in the treatment group and 39.1% in the control group. The difference between the two groups was statistically significant (P0.05); Two groups of patients before and after treatment blood gas index comparison, two groups of patients before treatment hypoxia and CO2 retention was obvious, two groups after treatment blood gas analysis indexes were improved, compared with before treatment, the difference was statistically significant (P0.05). Conclusion mannitol, citicoline combined with traditional Chinese medicine for the treatment of pulmonary encephalopathy has the advantages of convenience, simplicity, good curative effect, no toxic and side effects, easy to accept and so on. It is worth popularizing and applying in clinical practice.
【作者单位】：山东省曹县中医院;
【分类号】：R747.9

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