两种方式治疗大脑中动脉狭窄的疗效与安全性比较

发布时间：2019-04-16 17:52

【摘要】：目的比较血管内支架成形术与内科方式治疗青年严重症状性大脑中动脉狭窄患者脑卒中二级预防的疗效及安全性。方法收集该院2011年1月至2015年6月经全脑血管造影术明确的严重症状性大脑中动脉狭窄(狭窄率大于或等于70%)患者77例,分为血管内支架成形术组和内科治疗组,评估入院时改良Rankin评分(mRS评分)、美国国立卫生院卒中量表(NIHSS)评分及入组后1年内mRS评分和缺血性卒中复发、死亡、脑出血事件。结果血管内支架成形术组与内科治疗组30d内主要终点事件发生率分别为0%、5.77%,1年内卒中复发率分别为4.35%、13.46%,两组比较差异无统计学意义(P0.05)。两组均无死亡、脑出血发生。血管内支架成形术组与内科治疗组随访1年时mRS≤1分患者比例分别为91.30%、69.23%,两组比较差异有统计学意义(P0.05);mRS≤2分的患者分别为95.65%、84.62%,两组比较差异无统计学意义(P0.05)。结论血管内支架成形术在严重症状性大脑中动脉狭窄是安全的,对降低青年再发卒中风险比内科治疗更有效。
[Abstract]:Objective to compare the efficacy and safety of endovascular stenting and internal medicine for secondary prevention of stroke in young patients with severe symptomatic middle cerebral artery stenosis. Methods from January 2011 to June 2015, 77 patients with severe symptomatic middle cerebral artery stenosis (stenosis rate greater than or equal to 70%) were divided into two groups: endovascular stenting group and medical treatment group. The modified Rankin score (mRS score), the (NIHSS) score of the National Institutes of Health Stroke scale (NHS) and the mRS score and ischemic stroke recurrence, death and intracerebral hemorrhage events within 1 year after admission were evaluated. Results the incidence of major end-point events was 0%, 5.77% and 4.35%, 13.46% in endovascular stenting group and internal medicine group, respectively, and the recurrence rate of stroke within one year was 4.35% and 13.46%, respectively. There was no significant difference between the two groups (P0.05). There was no death and cerebral hemorrhage occurred in both groups. The percentage of patients with mRS 鈮，

本文编号：2458975