狼疮性脑病：狼疮性脑病4例报告并文献复习
发布时间：2019-06-15 04:34
【摘要】：目的探讨狼疮性脑病的临床特点及诊治 方法回顾性分析2012-2013年间我院神经内科收治的4例狼疮性脑病病例资料,并结合文献进行复习。 设计病例报告 病例4例病例均为女性,年龄在27-43岁间,2例有系统性红斑狼疮病史,其余2例均为初次在我科诊断并治疗。 干预4例均给予糖皮质激素激素及免疫抑制剂治疗,其中2例给予细胞毒性药物,1例给予静脉用丙种球蛋白及升压、呼吸兴奋剂等抢救治疗。 结果3例患者康复出院,1例因病情进行性加重,终抢救无效死亡。 结论狼疮性脑病是系统性红斑狼疮的严重并发症,死亡率较高。早期诊断,及时治疗,能够改善系统性红斑狼疮的预后,降低死亡率。
[Abstract]:Objective to investigate the clinical characteristics, diagnosis and treatment of lupus encephalopathy (Lupus Encephalopathy). To analyze the data of 4 cases of Lupus Encephalopathy treated in Department of Neurology in our hospital from 2012 to 2013, and to review the literature. All 4 cases reported in the design were female, aged between 27 years and 43 years old, 2 cases had a history of systemic lupus erythematosus, and the other 2 cases were diagnosed and treated in our department for the first time. All 4 cases were treated with glucocorticoid and immunosuppressant, 2 cases were treated with cytotoxicity drugs, 1 case was treated with intravenous gamma globulin, pressor, respiratory stimulant and so on. Results three patients recovered and discharged from hospital, 1 patient died of progressive aggravation. Conclusion Lupus Encephalopathy is a serious complication of systemic lupus erythematosus (SLE), and the mortality rate is high. Early diagnosis and timely treatment can improve the prognosis of systemic lupus erythematosus and reduce mortality.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R593.241;R747.9
本文编号：2499966
[Abstract]:Objective to investigate the clinical characteristics, diagnosis and treatment of lupus encephalopathy (Lupus Encephalopathy). To analyze the data of 4 cases of Lupus Encephalopathy treated in Department of Neurology in our hospital from 2012 to 2013, and to review the literature. All 4 cases reported in the design were female, aged between 27 years and 43 years old, 2 cases had a history of systemic lupus erythematosus, and the other 2 cases were diagnosed and treated in our department for the first time. All 4 cases were treated with glucocorticoid and immunosuppressant, 2 cases were treated with cytotoxicity drugs, 1 case was treated with intravenous gamma globulin, pressor, respiratory stimulant and so on. Results three patients recovered and discharged from hospital, 1 patient died of progressive aggravation. Conclusion Lupus Encephalopathy is a serious complication of systemic lupus erythematosus (SLE), and the mortality rate is high. Early diagnosis and timely treatment can improve the prognosis of systemic lupus erythematosus and reduce mortality.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R593.241;R747.9
【参考文献】
相关期刊论文 前3条
1 尹培达;重症系统性红斑狼疮的治疗[J];新医学;2000年01期
2 马林,安宁豫,高元桂,蔡幼铨,梁燕,郭行高,梁丽,李宏军;系统性红斑狼疮脑病的磁共振影像表现[J];中华放射学杂志;1998年11期
3 常巨平;刘岩;;小剂量环磷酰胺、甲基强的松龙治疗狼疮性脑病[J];医学研究通讯;2001年05期
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