后处理工艺对阳极氧化钛生物活性的影响

发布时间：2018-01-04 09:30

本文关键词：后处理工艺对阳极氧化钛生物活性的影响　出处：《功能材料》2015年01期 　论文类型：期刊论文

【摘要】：钛及钛合金由于具有良好的力学、生物学性能,已成为良好的骨修复和替换材料。为了改善钛的生物活性,首先采用两步电化学阳极氧化法对金属纯钛进行表面改性,即使之表面形成多孔纳米结构,然后对样品进行不同的后处理,如450℃热处理,NaOH处理,NaOH-CaCl2处理,最后将后处理样品浸泡在人体模拟液(SBF)中,研究磷灰石在样品表面的生长情况。采用X射线衍射(XRD)、带能量散射谱(EDS)的场发射扫描电子显微镜(FE-SEM)、傅里叶变换红外光谱(FT-IR)、电感耦合等离子体发射光谱仪(ICP-OES)等对生成的磷灰石的物相、形貌、元素组成等进行表征。结果表明,非晶TiO2纳米管阵列不能诱导磷灰石在其表面生成,而经450℃退火处理后形成的结晶良好的锐钛矿相TiO2纳米管阵列具有一定生物活性,即可诱导部分磷灰石颗粒在其表面生成。进一步经NaOH-CaCl2溶液后处理可加速羟基磷灰石在样品表面的形成速度,样品在模拟体液(SBF)中浸泡8d后,表面生成的磷灰石厚度约为5μm,磷灰石层是由大量球形颗粒堆积而成的,而球形颗粒是由无数纳米薄片组成的花状结构。
[Abstract]:Titanium and titanium alloy has good mechanical and biological performance, has become a good bone repair and replacement materials. In order to improve the biological activity of titanium, the two step anodization of pure titanium metal surface modification, even formed in the surface of nano porous structure, and then the samples were different postprocessing such as 450 DEG C, heat treatment, NaOH treatment, NaOH-CaCl2 treatment, the postprocessing samples were soaked in the simulated body liquid (SBF), on the growth of apatite in the sample surface. By using X ray diffraction (XRD), energy dispersion spectra (EDS) field emission scanning electron microscopy (FE-SEM), Fourier transform transform infrared spectroscopy (FT-IR), inductively coupled plasma emission spectrometer (ICP-OES) on the formation of apatite phase, morphology, element composition were characterized. The results show that the amorphous TiO2 nanotubes could not induce apatite on its surface Surface generation, crystallization and annealing at 450 C after the formation of good anatase TiO2 nanotube arrays have certain biological activity, can induce apatite particles on the surface generated by NaOH-CaCl2 solution. Further postprocessing can accelerate the formation of hydroxyapatite on the surface of the sample, the samples in simulated body fluid (SBF) immersion in 8D. The thickness of the apatite formed on the surface of about 5 mu m, apatite layer is composed of a large number of spherical particles accumulation, and spherical particles is a flower shaped structure composed of numerous nanosheets.

【作者单位】：同济大学材料科学与工程学院先进土木工程材料教育部重点实验室;
【基金】：上海市纳米专项基金资助项目(11nm0500700) 2012年上海市大学生创新活动计划资助项目(0500-107-034)
【分类号】：R318.08
【正文快照】： 1引言生物相容性材料是材料科学中的一个正在发展的新领域,不仅技术含量和经济价值高,而且与人类的生命和健康密切相关。随着生物相容性材料需求的增加,人们对新型生物相容性材料的研究与开发也日益激烈。金属生物医学材料是开发最早,应用最为广泛的植入性生物相容性材料之一

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