新型ALG-g-Lys微胶珠的制备工艺优化
发布时间:2018-02-07 15:08
本文关键词: 赖氨酸接枝海藻酸盐 微胶珠 正交设计 优化 出处:《化工进展》2014年09期 论文类型:期刊论文
【摘要】:为了提高海藻酸钙胶珠的稳定性,采用海藻酸盐的改性材料ALG-g-Lys制备微胶珠,通过单因素考察结合正交设计优化了ALG-g-Lys微胶珠的制备工艺。优化后的制备工艺为:ALG-g-Lys浓度为15g/L,电压为8.0kV,推进速度为30mm/h,针头型号为24G,CaCl2浓度为15g/L。优化后制得的微胶珠粒径均匀,球形度好,拖尾率、半球率和小球率小,平均粒径为253±40μm。该工作提供了一种新型的载体材料替代海藻酸盐作为凝胶材料,未来可适用于医药、食品行业等领域。
[Abstract]:In order to improve the stability of calcium alginate beads, microgel beads were prepared by ALG-g-Lys, a modified material of alginate. The preparation process of ALG-g-Lys microgel beads was optimized by single factor investigation and orthogonal design. The optimized preparation process was as follows: the concentration of w ALG-g-Lys was 15 g / L, the voltage was 8.0 kV, the propulsion speed was 30 mm / h, and the needle type was 24 g / L with a concentration of 15 g / L. The average particle size is 253 卤40 渭 m. This work provides a new carrier material instead of alginate as gel material, which can be used in medicine, food industry and other fields in the future.
【作者单位】: 华侨大学化工学院;
【基金】:国家自然科学基金(31000441、31170939) 福建省自然科学基金(2013J01189) 华侨大学校级科研基金(10HZR10)项目
【分类号】:R318.08
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