人体肺部组织复阻抗特性研究

发布时间：2018-03-10 15:42

本文选题：肺癌组织　切入点：复电阻抗　出处：《生物医学工程学杂志》2014年03期 　论文类型：期刊论文

【摘要】：为研究人体正常肺组织和肺癌组织复阻抗及特征参数随离体时间的变化规律,并建立肺部复阻抗实虚部对照图,为基础医学和临床诊断提供理论依据和数据参考,并为电阻抗断层成像技术(EIT)研究提供先验信息。本实验将手术切下的人体正常肺组织和肺癌组织放入测试箱中,控制测试箱的温度和湿度,控制并保持离体时间分别为30、60、80min,采用Agilent 4294A阻抗分析仪在频率为1 000Hz~30MHz范围内对人体正常肺组织和肺癌组织复阻抗进行测量。实验结果显示,在所测量的范围及对应的离体时间内,随离体时间延长,正常肺组织和肺癌组织的复阻抗均发生显著变化,但正常肺组织的阻抗值大于肺癌组织。该变化与细胞外液、细胞内液、细胞膜的变化相关。
[Abstract]:In order to study the changes of complex impedance and characteristic parameters of human normal lung tissue and lung cancer tissue with time in vitro, and to establish a control chart of complex impedance deficiency in lung, and to provide theoretical basis and data reference for basic medicine and clinical diagnosis. In this study, the normal lung tissue and lung cancer tissue were put into the test box, and the temperature and humidity of the test box were controlled. Agilent 4294A impedance analyzer was used to measure the complex impedance of normal human lung tissue and lung cancer tissue in the frequency range of 1 000 Hz for 80 min. The results showed that the measured range and the corresponding time in vitro were measured. The complex impedance of normal lung tissue and lung cancer tissue changed significantly with the prolongation of time in vitro, but the impedance value of normal lung tissue was higher than that of lung cancer tissue, which was related to the changes of extracellular fluid, intracellular fluid and cell membrane.
【作者单位】：天津大学电气与自动化工程学院;天津医科大学总医院放疗科;
【基金】：国家自然科学基金资助项目(50937005) 天津科委基金资助项目(12JCYBJC19500);天津科委基金资助项目(08JCYBJC03500)
【分类号】：R318.0

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