脊髓受压损伤机制的三维有限元分析

发布时间：2018-06-24 21:44

本文选题：脊髓 + 爆裂骨折　；参考：《医用生物力学》2014年04期

【摘要】：目的建立胸腰段脊髓的三维有限元模型,通过生物力学实验研究爆裂骨折时脊髓损伤的机制。方法利用有限元仿真技术,对爆裂骨折时脊髓受压情况进行仿真模拟,并通过与已经验证的模型及体内、体外实验结果相对比的方式对仿真结果进行检验。结果在爆裂骨折初期,脊髓白质的应变高于灰质。随着骨碎片位移的增加,灰质的应变逐渐上升,最终在骨碎片位移达到峰值时,白质的应变高于灰质。结论脊柱发生爆裂骨折时,脊髓损伤的严重程度取决于脊髓后部组织的受累情况。脊髓前角(运动功能区)和后角(感觉功能区)发生创伤的顺序也对脊髓损伤的程度有重要影响。临床上,可以通过评估脊髓运动功能区和感觉功能区发生损伤的严重程度,更加准确判断患者病情。对于脊髓损伤过程中应变分布的进一步研究,能够在应对脊髓损伤时采取更为有效的治疗与预防措施。
[Abstract]:Objective to establish a three-dimensional finite element model of thoracolumbar spinal cord and to investigate the mechanism of spinal cord injury in burst fracture by biomechanical experiments. Methods the compression of spinal cord in burst fracture was simulated by finite element simulation technique, and the simulation results were compared with the experimental results in vivo and in vitro. Results at the initial stage of burst fracture, the strain of white matter of spinal cord was higher than that of gray matter. With the increase of bone fragment displacement, the strain of gray matter increases gradually, and the strain of white matter is higher than that of gray matter at the peak of bone fragment displacement. Conclusion when spinal burst fracture occurs, the severity of spinal cord injury depends on the involvement of posterior spinal cord. The order in which the anterior horn of spinal cord (motor functional area) and the posterior horn (sensory functional area) occur also has an important effect on the degree of spinal cord injury. Clinically, the severity of injury in the motor and sensory areas of the spinal cord can be evaluated more accurately. Further study on the strain distribution during spinal cord injury can take more effective treatment and prevention measures in dealing with spinal cord injury.
【作者单位】：第四军医大学西京医院骨科;解放军63888部队;
【基金】：国家自然科学基金资助项目(81301292)
【分类号】：R318.01

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