组织工程的诞生与发展——组织工程连载之一

发布时间：2018-10-18 16:25

【摘要】：传统器官移植受到器官来源、伦理以及机体免疫排斥等方面的限制而难以满足临床治疗需要。为了应对不断的挑战,组织工程得以诞生和发展。最初组织工程的含义是联合使用细胞、支架材料和生物活性因子以促进组织的修复和再生方面的研究和应用,随着研究的深入组织工程的概念得到不断发展。现代组织工程学是一门利用工程学和生命科学的原理,研究和开发具有生物活性的人工替代物,以维持、恢复或提高人体受损组织的功能的交叉学科。自诞生20多年来,组织工程的发展大致经历了三个阶段。再生医学是现代临床医学的重要分支,与干细胞和组织工程具有密切的联系。组织工程是完美的组织器官再生,是再生医学的关键研究领域,体现了再生医学的主要发展方向。再生医学的理论和技术方法促进了组织工程的发展。
[Abstract]:Traditional organ transplantation is limited by organ source, ethics and immune rejection, so it is difficult to meet the need of clinical treatment. In order to meet the constant challenges, organizational engineering has been born and developed. The original meaning of tissue engineering was to combine cell, scaffold materials and bioactive factors to promote the research and application of tissue repair and regeneration, and the concept of tissue engineering was developed with the development of research. Modern tissue engineering is an interdisciplinary subject which uses the principles of engineering and life science to study and develop artificial substitutes with biological activity to maintain restore or improve the function of damaged tissues of human body. Since the birth of more than 20 years, the development of tissue engineering has undergone three stages. Regenerative medicine is an important branch of modern clinical medicine, which is closely related to stem cells and tissue engineering. Tissue engineering is the perfect tissue and organ regeneration, is the key research field of regenerative medicine, and embodies the main development direction of regenerative medicine. The theory and technical methods of regenerative medicine promote the development of tissue engineering.
【作者单位】：第二炮兵总医院药学部组织工程与再生医学实验室;
【分类号】：R318

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