磁耦合驱动搏动式血泵的可行性研究

发布时间：2018-10-19 11:58

【摘要】：目的提出一种磁耦合驱动搏动式血泵结构并验证其可行性。方法基于磁场传递往复作用力模型以及推拉互挽式结构设计磁耦合驱动搏动血泵,通过建立磁力驱动模型,计算耦合力大小,制作样机并对样机进行体外循环模拟试验,获得压力和流量实验数据。结果采用生理盐水作为循环介质,固定后负荷,增加前负荷,血泵输出量减少,没有明显线性趋势;固定前负荷,增加后负荷,血泵输出量减少,且具有一定线性趋势。设置驱动频率为75次/min时,调节前、后负荷改变范围分别为0.665~3.990 k Pa(5~30 mm Hg)和5.320~11.970 k Pa(5~30 mm Hg),可使输出量在保证线性关系条件下达到2.0~3.1 L/min。结论该搏动式血泵流体力学特性基本满足体外膜肺循环的需要,仍需进一步研究和改进;研究结果具有重要的应用前景,尤其对替代目前临床体外膜肺氧合设备的血泵装置具有重要意义。
[Abstract]:Objective to propose a magnetic coupling driven pulsatile blood pump and verify its feasibility. Methods the magnetic coupling pulsatile blood pump was designed based on the magnetic field transfer reciprocating force model and the push-pull reciprocal pull structure. The magnetic force driving model was established, the coupling force was calculated, the prototype was made and the prototype was simulated by extracorporeal circulation. Pressure and flow data are obtained. Results when physiological saline was used as circulation medium, the output of blood pump decreased with the increase of preload, while the output of blood pump decreased with the increase of load before fixation and decreased with the increase of afterload, and the output of blood pump showed a certain linear trend. When the driving frequency is 75 times / min, before adjusting, the range of afterload change is 0.665 ~ 3.990 k Pa (_ 5 ~ 30 mm Hg) and 5.320 ~ 11.970 k Pa (_ 5 ~ 30 mm Hg), respectively, and the output can reach 2.0 ~ 3.1L / min under the condition of guaranteed linear relation. Conclusion the hydrodynamic characteristics of the pulsatile blood pump can meet the needs of CPB, and need to be further studied and improved. Especially, it is of great significance to replace the current extracorporeal membrane pulmonary oxygenation equipment.
【作者单位】：上海理工大学医疗器械与食品学院;上海市东医院危重症医学科;
【基金】：上海大学生创新活动计划项目(SH2013135)
【分类号】：R197.39

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