硫酸钙骨替代材料联合椎弓根钉固定恢复胸腰椎压缩骨折椎体高度

发布时间：2018-12-26 19:17

【摘要】：背景:硫酸钙骨替代材料具有良好的安全性和生物相容性,植入人体后具备较好的强度,可恢复胸腰椎骨折力学强度,降低椎体高度的丢失且可逐渐被降解吸收。目的:观察硫酸钙骨替代材料联合后路椎弓根钉固定恢复胸腰椎压缩骨折椎体高度的效果。方法:纳入42例T12-L3胸腰椎压缩骨折患者,其中男27例,女15例,年龄21-57岁,均实施硫酸钙骨替代材料联合后路椎弓根钉固定置入治疗,治疗后12个月,对比治疗前后的椎体前缘高度、脊柱后凸Cobb角、Oswestry功能障碍指数评分及目测类比评分情况。结果与结论:随访12个月,所有患者均未出现局部炎症和过敏、刺激反应等,未发生凝血改变和免疫反应等,螺钉无断裂或者松动现象;末次随访椎体前缘高度较治疗前显著增加(P0.05),末次随访脊柱后凸Cobb角、Oswestry功能障碍指数及目测类比评分较治疗前显著减小(P0.05)。表明硫酸钙骨替代材料联合后路椎弓根钉固定置入治疗可显著恢复胸腰椎压缩骨折患者的椎体高度,促进患者功能恢复。
[Abstract]:Background: calcium sulfate bone substitute material has good safety and biocompatibility. It can restore the mechanical strength of thoracolumbar fractures and reduce the loss of vertebral height and be gradually degraded and absorbed. Objective: to observe the effect of calcium sulfate bone replacement material combined with posterior pedicle screw fixation in restoring vertebral body height of thoracolumbar compression fracture. Methods: 42 cases of T12-L3 thoracolumbar vertebral compression fracture, including 27 males and 15 females aged 21-57 years, were treated with calcium sulfate bone replacement material and posterior pedicle screw fixation. The anterior height of vertebral body, Cobb angle of kyphosis, Oswestry dysfunction index and visual analogue score were compared before and after treatment. Results and conclusion: all the patients were followed up for 12 months without local inflammation, allergic reaction, irritation, coagulation and immune reaction, and no breakage or loosening of screw. The anterior height of vertebral body in the last follow-up was significantly higher than that before treatment (P0.05). The Cobb angle of kyphosis, Oswestry dysfunction index and visual analogue score were significantly decreased in the last follow-up compared with those before treatment (P0.05). The results showed that calcium sulfate bone replacement material combined with posterior pedicle screw fixation could significantly restore the vertebral body height of patients with thoracolumbar compression fracture and promote the functional recovery of the patients.
【作者单位】：南方医科大学附属医院顺德第一人民医院骨科一区;
【分类号】：R687.3;R318.08

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