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可吸收缝合线的线径在线检测及控制技术

发布时间:2019-03-10 17:54
【摘要】:壳聚糖-胶原蛋白可吸收缝合线由于其可塑性强、组织相容性好及可降解的特性,被广泛地应用在需要内缝合的手术中。而在缝合线成形和缠绕过程中,对缝合线线径进行检测及控制是保证线径均匀和抗张强度不变的前提。传统的纺丝成形工艺山于缺乏对纺丝工艺关键技术的掌握,喷丝速度不易控制,导致成形后的可吸收缝合线线径粗细不均,严重影响其推广应用。传统测量是在缝合线实验台上进行离线测量,测量周期长、速度慢,无法实现闭环控制。本文研究一种可吸收缝合线的线径在线检测与控制技术,实现在纺丝成形过程中对线径进行闭环控制及在线检测,提升控制系统精度,保证成品壳聚糖-胶原蛋白可吸收缝合线线径均匀。可吸收缝合线纺丝成形中的线径闭环控制系统包括核心控制模块、喷丝装置、线径检测模块三部分。其中线径检测模块通过对待测缝合线进行光学成像,由基于ARM Cortex-M3核心的32位微控制器STM32F103ZET6驱动线阵CCD图像传感器TCD1209D对光强信息进行采集,将采集的电信号通过信号调理后由片内AD进行A/D转换,通过采用基于遗传算法的二值化图像分割的方法进行数据处理,再经过线径计算,最终获得可吸收缝合线的线径测量值,实现线径的在线测量。设计一种以反串联双液压缸为主体结构的喷丝装置,通过线径检测模块获得壳聚糖-胶原蛋白可吸收缝合线的线径测量值,将线径测量值送入以STM32F103ZET6为核心的控制模块中,由改进的广义预测控制算法控制喷丝装置中直流伺服电机的转速,进而调节喷嘴的喷丝速度,获得与线径设定值一致的初生态丝。初生态丝经一系列工艺流程后获得成品的可吸收缝合线,实现对壳聚糖-胶原蛋白可吸收缝合线成形过程中线径的闭环控制。可吸收缝合线的线径在线检测与控制技术实现了针对可吸收缝合线的非接触式在线测量,完成了在纺丝成形过程中的闭环控制,同时保证了成品可吸收缝合线的线径符合中华人民共和国医药行业标准YY1116-2010《可吸收性外科缝线》的要求,系统误差精度可控制在2%内,成品可吸收缝合线线径均匀。本论文在提升国内医疗水平和针对缝合线的科学研究方面具有重要意义。
[Abstract]:Chitosan-collagen absorbable suture is widely used in internal suture because of its good plasticity, good histocompatibility and biodegradability. In the process of stitch forming and winding, the measurement and control of stitch diameter is the premise to ensure uniform diameter and constant tensile strength. The traditional spinning process is inferior to the lack of master of the key technology of spinning technology, and the speed of spinning is not easy to control, which results in the uneven diameter of absorbable stitch after forming, which seriously affects its popularization and application. The traditional measurement is off-line measurement on the sewing line experimental platform. The measurement period is long and the speed is slow, so the closed-loop control can not be realized. In this paper, a kind of on-line measurement and control technology for the diameter of absorbable stitches is studied. The closed-loop control and on-line detection of the diameter of the wire are realized in the spinning process, and the precision of the control system is improved. The final chitosan-collagen can be absorbed and sutured evenly in diameter. The closed loop control system of wire diameter in absorbable stitch spinning is composed of three parts: core control module, spinneret device and wire diameter detection module. In the line diameter detection module, optical imaging is carried out by treating the seam line, and the light intensity information is collected by the linear CCD image sensor TCD1209D driven by the 32-bit microcontroller STM32F103ZET6 based on the core of ARM Cortex-M3, which is driven by the linear CCD image sensor TCD1209D. The collected electrical signals are converted by on-chip AD after signal conditioning. The data are processed by binary image segmentation method based on genetic algorithm, and then the line diameter is calculated. Finally, the line diameter measurement value of the absorbable suture is obtained, and the on-line measurement of the line diameter is realized. A wire spraying device with double hydraulic cylinders in reverse series is designed. The wire diameter measurement value of chitosan-collagen absorbable suture is obtained by wire diameter detection module, and the wire diameter measurement value is put into the control module with STM32F103ZET6 as the core. The improved generalized predictive control (GPC) algorithm is used to control the rotational speed of the DC servo motor in the spinneret, and then to adjust the jet speed of the nozzle, and to obtain the primary ecological filament which is consistent with the setting value of the wire diameter. The absorbable suture of the finished product was obtained by a series of technological processes, and the closed-loop control of the diameter of the absorbable suture was realized during the process of forming chitosan-collagen absorbable suture. The non-contact on-line measurement of absorbable suture is realized by the on-line measurement and control of the diameter of the absorbable suture, and the closed-loop control in the spinning process is completed. At the same time, the diameter of absorbable suture can meet the requirements of YY1116-2010 (absorbable surgical suture), the precision of system error can be controlled within 2%, and the diameter of absorbable suture is uniform. This paper is of great significance in improving the level of domestic medical treatment and scientific research on suture.
【学位授予单位】:天津工业大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R318.08

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