生物源组织工程支架材料研究进展

发布时间：2019-04-27 00:39

【摘要】：目的总结生物源组织工程支架材料的研究进展,结合临床应用及产品研发现况讨论该行业的发展瓶颈及应对策略。方法基于对生物源组织工程支架材料研究和应用的广泛调研,综合分析其研发、应用现况,对该领域的研究、产品开发等现况进行剖析。结果生物衍生材料、脱细胞基质以及细胞外基质等生物源组织工程支架材料在研究、产业转化、临床应用和监管等领域均已取得长足进步,新方向、新产品、新技术仍在不断涌现。随着科学技术不断进步以及生命科学理论的不断完善,生物源组织工程支架材料的新方向、新重点仍需进行不断调整以满足临床需求。结论从产业转化可行性而言,脱细胞支架和细胞外基质最有望成为该领域研究和产品开发的新增长点。
[Abstract]:Aim to summarize the research progress of biomaterial scaffold materials for tissue engineering, and discuss the bottleneck and countermeasures of the industry in the light of clinical application and product research and development. Methods based on the extensive investigation on the research and application of scaffold materials for tissue engineering of biological sources, the current status of research and development and application of scaffolds were comprehensively analyzed, and the current situation of research in this field, product development and so on were analyzed. Results Biological derived materials, acellular matrix and extracellular matrix have made great progress in the fields of research, industrial transformation, clinical application and supervision, and have made great progress in the new direction, new products, and other biological tissue engineering scaffolds, such as bio-derived materials, acellular matrix and extracellular matrix, and so on. New technologies are still emerging. With the development of science and technology and the improvement of life science theory, the new direction of biological tissue engineering scaffolds needs to be adjusted to meet the clinical needs. Conclusion as far as the feasibility of industrial transformation is concerned, acellular scaffolds and extracellular matrix are most likely to be new growth points of research and product development in this field.
【作者单位】：北京大学前沿交叉学科研究院;北京大学工学院;
【基金】：“十二五”国家“863”计划主题项目(2012AA020502)~~
【分类号】：R318.08

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