测量生物组织等效杨氏模量的毫米压痕仪
发布时间：2019-06-04 22:47
【摘要】：生物组织的弹性是诊断其是否发生病变的重要依据,杨氏模量是反映组织弹性的重要参数。以Labview为软件平台结合数据采集和运动控制等硬件设备,研制了一套测量弹性模量的毫米压痕弹性仪。以市购冷鲜牛肉、猪肉、猪肝和猪肾为试样,测量了球形压头向试样施加的负载力和对应的试样压痕深度,在对测量数据进行校准的基础上,利用基于赫兹接触力学模型的压头半径R、作用力F、压痕深度δ与试样等效杨氏模量E~*间的解析关系,得到各试样的等效杨氏模量。实验结果表明,测得的组织试样等效杨氏模量数值与文献基本相符,所设计的毫米级压痕法测试装置可用于生物组织等效杨氏模量的检测。
[Abstract]:The elasticity of biological tissue is an important basis for the diagnosis of pathological changes, and Young's modulus is an important parameter to reflect the elasticity of tissue. Based on Labview software platform and hardware equipment such as data acquisition and motion control, a millimeter indentation elastic instrument for measuring elastic modulus is developed. Taking cold fresh beef, pig liver and pig kidney as samples, the load force applied by spherical indentation head to the sample and the corresponding indentation depth were measured. On the basis of calibration of the measured data, Based on the Hertz contact mechanics model, the equivalent Young's modulus of each sample is obtained by using the analytical relationship between the indentation radius R, the force F, the indentation depth 未 and the equivalent Young's modulus of the sample. The experimental results show that the equivalent Young's modulus of the tissue sample is in good agreement with that of the literature, and the millimeter grade indentation method can be used to detect the equivalent Young's modulus of biological tissue.
【作者单位】： 中国科学院声学研究所东海研究站;长春理工大学机电工程学院;
【基金】：国家自然科学基金资助项目(11274342、11474042、11304353、11574348)
【分类号】：R318.6
本文编号：2493057
[Abstract]:The elasticity of biological tissue is an important basis for the diagnosis of pathological changes, and Young's modulus is an important parameter to reflect the elasticity of tissue. Based on Labview software platform and hardware equipment such as data acquisition and motion control, a millimeter indentation elastic instrument for measuring elastic modulus is developed. Taking cold fresh beef, pig liver and pig kidney as samples, the load force applied by spherical indentation head to the sample and the corresponding indentation depth were measured. On the basis of calibration of the measured data, Based on the Hertz contact mechanics model, the equivalent Young's modulus of each sample is obtained by using the analytical relationship between the indentation radius R, the force F, the indentation depth 未 and the equivalent Young's modulus of the sample. The experimental results show that the equivalent Young's modulus of the tissue sample is in good agreement with that of the literature, and the millimeter grade indentation method can be used to detect the equivalent Young's modulus of biological tissue.
【作者单位】： 中国科学院声学研究所东海研究站;长春理工大学机电工程学院;
【基金】：国家自然科学基金资助项目(11274342、11474042、11304353、11574348)
【分类号】：R318.6
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