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基于顺磁特性的氧气浓度测量系统的研制

发布时间:2019-06-14 18:25
【摘要】:氧气是人体呼吸、促进人体机体代谢不可缺少的一种气体,机体细胞正常活动有赖于持续不断的氧供给,恰当的氧供给决定心、肺及血液系统功能的协调。而针对呼吸系统中的FiO2、EtO2、FiCO2与EtCO2等参数的监测可以反映整个呼吸循环系统的功能状况,特别是在手术应用中,氧气浓度与二氧化碳浓度的监测能够帮助医生对病人的生理状态与仪器的正常使用进行初步判断,对医生的操作有着指导作用,这些应用可有效地提高手术的安全性,保证手术正常有序的进行下去,所以氧气与二氧化碳气体浓度的监测有着十分重要的意义。目前国内对于氧气浓度监测技术及应用方面十分缺乏,尤其是在顺磁氧浓度监测技术方面基本处于空白状态,因此本文提出研制一种顺磁氧气测量模块,并与旁流式二氧化碳气体浓度测量模块集成以形成氧气和二氧化碳同步测量系统。本文首先根据目前国内外的氧气测量方法与二氧化碳气体浓度监测技术的发展现状与应用技术做了调研,对比各个方法的优缺点。在介绍了医用氧气浓度监测在临床应用的价值与现有的各个测量方法的同时还介绍了国内外的发展现状与现在市场上主流的部分产品,进一步详细介绍了现有氧气监测的方法及其特点,介绍了顺磁法氧气浓度监测的原理和实现方法,以此提出了本文拟研制的氧气监测系统的设计方案,并从系统机械设计、系统硬件设计、模块软件设计与PC机评估软件设计等四个方面完成整个监测系统的设计。其中系统机械设计包括了整个测量模块的气室设计与气室内部管路的设计。系统硬件设计的内容包括整体模块中关键器件的选型与关键器件的订制,还包括电源模块、传感器信号放大滤波模块、信号采集模块与数字部分电路组成,其中信号采集模块采用的是外部24位高精度ADC,数字电路中的主CPU为意法半导体公司的STM32F103系列的单片机。模块软件的设计包括了电磁线圈的驱动与外部高精度AD的控制等部分,PC机评估软件的功能是显示模块的工作状态与各个参数的数值,可以响应下位机软件的命令也可以下发命令到下位机软件部分。算法处理部分详细介绍了氧气浓度值的计算与校准实现,还对温度影响进行补偿算法的研究。最后对于本课题研制的氧气与二氧化碳浓度测量模块的验证分为了两个主要部分,首先与国家医用电气设备呼吸气体监护仪的基本安全和主要性能专用要求内的相关要求进行了验证,后续与市场上的成熟产品对比了主要参数的性能。通过两个验证的结果显示,本文研制的测量系统拥有较好的稳定性与准确性,其中氧气的测量范围0-100%,测量精度为±1%,达到了相关标准的要求。最后总结目前本课题的成果,并对存在的不足与未来的改进方向进行说明。
[Abstract]:Oxygen is an indispensable gas to promote the metabolism of human body. The normal activity of cells depends on the continuous oxygen supply, and the proper oxygen supply determines the coordination of heart, lung and blood system functions. The monitoring of FiO2,EtO2,FiCO2 and EtCO2 in respiratory system can reflect the function of the whole respiratory and circulatory system, especially in surgical application, the monitoring of oxygen concentration and carbon dioxide concentration can help doctors to make a preliminary judgment on the physiological state of patients and the normal use of instruments, and plays a guiding role in the operation of doctors. These applications can effectively improve the safety of surgery. It is very important to monitor the concentration of oxygen and carbon dioxide to ensure the normal and orderly operation. At present, there is a great lack of oxygen concentration monitoring technology and its application in China, especially the paramagnetic oxygen concentration monitoring technology is basically blank. Therefore, this paper proposes to develop a paramagnetic oxygen measurement module, which is integrated with the side-flow carbon dioxide gas concentration measurement module to form a synchronous measurement system of oxygen and carbon dioxide. In this paper, the development status and application technology of oxygen measurement methods and carbon dioxide concentration monitoring technology at home and abroad are investigated, and the advantages and disadvantages of each method are compared. This paper introduces the clinical application value of medical oxygen concentration monitoring and the existing measurement methods, at the same time, it also introduces the development status at home and abroad and some mainstream products in the current market, further introduces the existing oxygen monitoring methods and their characteristics, introduces the principle and realization method of paramagnetism oxygen concentration monitoring, and puts forward the design scheme of the oxygen monitoring system to be developed in this paper. The design of the whole monitoring system is completed from four aspects: system mechanical design, system hardware design, module software design and PC evaluation software design. The mechanical design of the system includes the gas chamber design of the whole measurement module and the design of the internal pipeline of the gas chamber. The hardware design of the system includes the selection of the key devices in the whole module and the customization of the key devices, as well as the power supply module, the sensor signal amplification and filtering module, the signal acquisition module and the digital part circuit. The signal acquisition module adopts the main CPU of the external 24-bit high precision ADC, digital circuit as the STM32F103 series single chip microcomputer of Yifa Semiconductor Company. The design of the module software includes the drive of the electromagnetic coil and the control of the external high precision AD. The function of the PC evaluation software is to display the working state of the module and the value of each parameter. It can respond to the command of the lower computer software or send the command to the lower computer software. In the part of algorithm processing, the calculation and calibration of oxygen concentration value are introduced in detail, and the compensation algorithm for temperature influence is also studied. Finally, the verification of oxygen and carbon dioxide concentration measurement module developed in this paper is divided into two main parts. Firstly, it is verified with the basic safety and main performance requirements of the national medical electrical equipment respiratory gas monitor, and then the performance of the main parameters is compared with the mature products on the market. The results show that the measurement system developed in this paper has good stability and accuracy, in which the measurement range of oxygen is 0 鈮,

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