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In Vitro Biocompatibility of MC3T3-E1 Osteoblast-like Cells

发布时间:2021-08-20 01:28
  Carbon/carbon(C/C) composites were deposited with graphite-like carbon(GLC) coating, and then, Arg-GlyAsp acid(RGD) peptides were successfully immobilized onto the functionalized GLC coating. GLC coating was utilized to prevent carbon particles releasing and create a uniform surface condition for C/C composites. RGD peptides were utilized to improve biocompatibility of GLC coating. Surface chemical characterizations of functionalized GLC coating were detected by contact angle measurement, X-ray ... 

【文章来源】:Acta Metallurgica Sinica(English Letters). 2017,30(06)EISCICSCD

【文章页数】:9 页

【文章目录】:
1 Introduction
2 Materials and Methods
    2.1 C/C Composites
    2.2 GLC Coating Preparation
    2.3 Surface Modification of GLC-C/C
    2.4 RGD Peptides and its Immobilizing
    2.5 Surface Characterization
    2.6 Cell Culture and In Vitro Evaluation
    2.7 Cellular Morphology Observations
    2.8 Statistical Analysis
3 Results
    3.1 GLC Coating on C/C Composites
    3.2 Oxidized GLC Coatings
    3.3 Suitable Oxidation Temperature of GLC Coating for Immobilizing
    3.4 Cellular Morphology and Cytology Test of RGD Peptides Modified GLC-C/C Composites
4 Discussion
5 Conclusion



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