颞骨类癌6例临床分析

发布时间：2017-12-26 23:35

本文关键词：颞骨类癌6例临床分析　出处：《临床耳鼻咽喉头颈外科杂志》2016年19期 　论文类型：期刊论文

【摘要】：目的:总结分析颞骨类癌的临床特征、鉴别诊断及手术治疗方法。方法:回顾性总结分析6例经病理证实的颞骨类癌患者的临床资料,并复习相关文献。依据病变范围行颞骨次全切除手术或颞骨扩大切除术。结果:6例患者影像学资料示颞骨不同范围的占位病变,术后病理均为颞骨类癌,最终诊断为单侧原发性颞骨类癌。第1次手术后,面瘫复发2例,颅内转移1例。治疗后无并发症,随访5例无复发及远处转移,仅1例因肝转移死亡。结论:颞骨类癌临床上少见,无特征性临床及影像学表现,易与中耳炎或中耳其他良、恶性肿瘤混淆。确诊主要依靠病理及免疫组织化学。一般以手术治疗为主。早期发现并彻底切除肿瘤者转移和复发率低。
[Abstract]:Objective: To summarize and analyze the clinical features, differential diagnosis and surgical treatment of temporal bone like carcinoma. Methods: the clinical data of 6 patients with the pathologically confirmed temporal bone carcinoid were reviewed and analyzed, and the related literature was reviewed. Subtotal resection of the temporal bone or enlarged excision of temporal bone was performed on the basis of the lesion range. Results: the imaging data of 6 cases showed the occupying lesion of the temporal bone in different ranges, and the postoperative pathology was the type of the temporal bone carcinoid, and the final diagnosis was the primary primary temporal bone carcinoid. After the first operation, there were 2 cases of facial paralysis and 1 cases of intracranial metastasis. There were no complications after treatment. There were no recurrence and distant metastasis in 5 cases. Only 1 cases died of liver metastasis. Conclusion: the temporal bone carcinoid is rare in clinical, without characteristic clinical and imaging findings, and is easily confused with otitis media or other benign and malignant tumors of the middle ear. The diagnosis mainly depends on the pathology and immunohistochemistry. Generally, surgical treatment is the main treatment. The rate of metastasis and recurrence was low in the early detection and total resection of the tumor.
【作者单位】：中国人民解放军总医院耳鼻咽喉头颈外科;河西学院附属张掖人民医院耳鼻咽喉头颈外科;
【基金】：国家自然科学基金面上项目(No:81170908,81470683)
【分类号】：R739.6
【正文快照】： 类癌(carcinoid tumor)是一种具有上皮及神经内分泌双向分化的肿瘤,属于神经内分泌瘤(neuroendocrine tumor,NET)的一种,是少见的低度恶性肿瘤。多见于肺部、胰腺及胃肠道,颞骨类癌在临床上罕见。自Murphy等(1980)首次报道颞骨类癌后,国内外也只有零星报道,截至2010年国外共有

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