糖尿病足患者视网膜病变相关性研究

发布时间：2017-12-28 22:21

本文关键词：糖尿病足患者视网膜病变相关性研究　出处：《临床医药文献电子杂志》2016年40期 　论文类型：期刊论文

【摘要】：目的探讨糖尿病足与视网膜病变的相关性。方法选取我院2011年1月~2014年1月糖尿病足患者100例设为观察组,100例非糖尿病足患者设为对照组,观察两组患者视网膜病变的发生率及血浆纤维蛋白原(Fib)、C-反应蛋白水平(hs-CRP)水平。结果观察组100例糖尿病足患者,中轻、中度非增殖型视网膜病变33例,重度非增生性增殖型视网膜病变39例,增殖型视网膜病变19例,视网膜病变率为91%,对照组100例糖尿病未合并足病的患者中,中轻、中度非增殖型视网膜病变8例,重度非增殖型视网膜病变6例,增殖型视网膜病变1例,视网膜病变率为15%。两组患者视网膜病变率比较,差异有统计学意义(P0.05)。观察组患者Fib与hs-CRP较对照组均有明显上升,差异有统计学意义(P0.05)。结论糖尿病足与视网膜病变呈正相关,糖尿病足患者视网膜病变的发生与患者血浆纤维蛋白原、C-反应蛋白水平异常升高有着紧密的联系。
[Abstract]:Objective to investigate the relationship between diabetic foot and retinopathy. Methods a total of 100 patients with diabetic foot in our hospital from January 2011 to January ~2014 were selected as the observation group, and 100 patients without diabetic foot as the control group. The incidence of retinopathy and the levels of plasma fibrinogen (Fib) and C- reactive protein (hs-CRP) in two groups were observed. Results in the observation group, 100 cases of diabetic foot patients, mild to moderate non proliferative retinopathy in 33 cases, severe non proliferative proliferative retinopathy in 39 cases, 19 cases of proliferative retinopathy, retinopathy rate was 91%, the control group of 100 cases without diabetes foot disease patients, 8 cases of mild to moderate non proliferative retinopathy, 6 cases of severe non proliferative retinopathy, 1 cases of proliferative retinopathy, retinopathy rate was 15%. There was a significant difference in the rate of retinopathy in the two groups (P0.05). The Fib and hs-CRP in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P0.05). Conclusion diabetic foot is positively correlated with retinopathy. The occurrence of retinopathy in diabetic foot is closely related to the abnormal increase of plasma fibrinogen and C- reactive protein level.
【作者单位】：上海中医药大学附属上海市中西医结合医院;
【基金】：项目编号:虹卫1403-03
【分类号】：R587.2;R774.1
【正文快照】： 近年来,糖尿病在我国的发病率呈逐年上升的趋势[1],部分糖尿病患者在病程的推移过程中,会并发足部溃疡,也就是临床上常见的糖尿病足。糖尿病足患者最常见的并发症就是视网膜病变,为了探讨糖尿病足与视网膜病变的相关性,我院对糖尿病足患者的视网膜病变情况以及糖尿病未合并病

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