原发性急性闭角型青光眼脉络膜厚度变化及相关影响因素

发布时间：2018-01-01 05:34

本文关键词：原发性急性闭角型青光眼脉络膜厚度变化及相关影响因素　出处：《解放军预防医学杂志》2017年04期 　论文类型：期刊论文

【摘要】：目的探讨原发性急性闭角型青光眼(APACG)脉络膜厚度变化及相关影响因素。方法选取2015年1月—2015年12月在本院眼科门诊就诊的120例原发性急性闭角型青光患者,另选取同期行常规眼科检查的120例健康体检者为对照组,应用谱域相干断层深度增强扫描(EDI SD-OCT)测定两组脉络膜厚度,应用单因素及Logistic多因素分析影响APACG患者脉络膜厚度变化相关危险因素。结果APACG组脉络膜厚度、中心凹下脉络膜厚度较对照组薄(P0.001),两组眼轴长度、玻璃体长度、屈光度、前房深度、晶体厚度差异有统计学意义(P0.001)。经Pearson单因素分析显示,年龄、眼轴、屈光度与APACG组中心凹下脉络膜厚度呈负相关(r=-0.412,-0.358,-0.367,P0.05),与前房深度呈正相关(r=0.429,P0.05)。经Logistic分析显示,年龄、眼轴、屈光度数是影响APACG脉络膜厚度变薄的独立危险因子。结论APACG脉络膜厚度变化与部位有关,年龄、眼轴、屈光度数与APACG患者中心凹下脉络膜呈负相关,且是APACG脉络膜变薄的独立危险因素。
[Abstract]:Objective to investigate the APACGs of primary acute angle-closure glaucoma (ACG). Methods from January 2015 to December 2015, 120 patients with primary acute closed angle light were selected. In addition, 120 healthy persons who underwent routine ophthalmology examination were selected as control group. The choroidal thickness was measured by EDI SD-OCTs with spectral domain coherence tomography (SPECT). Single factor and Logistic multivariate analysis were used to analyze the risk factors of choroidal thickness change in APACG patients. Results the choroidal thickness in APACG group. The thickness of the subcentral fovea was thinner than that of the control group (P 0.001). The axial length, vitreous length, diopter and anterior chamber depth were observed in the two groups. The difference of lens thickness was statistically significant (P 0.001). Pearson univariate analysis showed that age and eye axis. There was a negative correlation between diopter and the thickness of central foveal choroid in APACG group. There was a positive correlation between the depth of anterior chamber and the depth of anterior chamber. The Logistic analysis showed that the age and the axial axis of the eyes. Diopter is an independent risk factor for the thinning of choroidal thickness in APACG. Conclusion the change of choroidal thickness in APACG is related to location, age and eye axis. There was a negative correlation between diopter and subcentral choroid in APACG patients, and it was an independent risk factor for APACG choroid thinning.
【作者单位】：解放军第四七四医院眼科;
【分类号】：R775.2
【正文快照】： 青光眼是全球第二大致盲疾病,根据青光眼类型可分为闭角型及开角型,我国以原发性闭角型青光眼居多,好发于50岁以上中老年人群,患者临床表现为眼压升高、视野缺损及特征性视神经功能损害[1]。脉络膜是眼内炎症主要受累组织,也是多种眼部疾病易于侵犯的组织。脉络膜作为人体眼

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